Metabolomic analysis revealed that female mussel Mytilus galloprovincialis was sensitive to bisphenol A exposures

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 中科院海岸带环境过程与生态修复重点实验室

	Metabolomic analysis revealed that female mussel Mytilus galloprovincialis was sensitive to bisphenol A exposures
	Ji, Chenglong1,2 ; Wei, Lei 1,2; Zhao, Jianmin1 ; Wu, Huifeng1
刊名	ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
	2014-03-01
卷号	37 期号:2 页码:844-849
关键词	Bisphenol A Mytilus galloprovincialis Toxicological effects Metabolomics
ISSN号	1382-6689
通讯作者	Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc,YICCAS, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
产权排序	[Ji, Chenglong; Wei, Lei; Zhao, Jianmin; Wu, Huifeng] Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc,YICCAS, Yantai 264003, Peoples R China; [Ji, Chenglong; Wei, Lei] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
中文摘要	Bisphenol A (BPA) is a synthetic compound used in numerous chemicals, such as polycarbonate plastics and epoxy resins, and it can be released into aquatic environment and poses risk on aquatic organisms. In this work, metabolomics was applied to characterize the metabolic responses in mussel Mytilus galloprovincialis exposed to BPA. Our results indicated that the gonad of female mussel was sensitive to BPA exposures (1 and 10 mu g/L) for one month. However, no significant metabolic responses were observed in male mussel gonads exposed to these two concentrations of BPA. Overall, this limited study suggested that the gender differences should be considered in marine ecotoxicology. (C) 2014 Elsevier B.V. All rights reserved.
英文摘要	Bisphenol A (BPA) is a synthetic compound used in numerous chemicals, such as polycarbonate plastics and epoxy resins, and it can be released into aquatic environment and poses risk on aquatic organisms. In this work, metabolomics was applied to characterize the metabolic responses in mussel Mytilus galloprovincialis exposed to BPA. Our results indicated that the gonad of female mussel was sensitive to BPA exposures (1 and 10 mu g/L) for one month. However, no significant metabolic responses were observed in male mussel gonads exposed to these two concentrations of BPA. Overall, this limited study suggested that the gender differences should be considered in marine ecotoxicology. (C) 2014 Elsevier B.V. All rights reserved.
学科主题	Environmental Sciences; Pharmacology & Pharmacy; Toxicology
研究领域[WOS]	Environmental Sciences & Ecology ; Pharmacology & Pharmacy ; Toxicology
关键词[WOS]	ENVIRONMENTALLY RELEVANT CONCENTRATIONS ; NMR-BASED METABOLOMICS ; RESPONSES ; HEALTH ; GILLS
收录类别	SCI
语种	英语
WOS记录号	WOS:000335636600040
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/8767]
专题	烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc,YICCAS, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Ji, Chenglong,Wei, Lei,Zhao, Jianmin,et al. Metabolomic analysis revealed that female mussel Mytilus galloprovincialis was sensitive to bisphenol A exposures[J]. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,2014,37(2):844-849.
APA	Ji, Chenglong,Wei, Lei,Zhao, Jianmin,&Wu, Huifeng.(2014).Metabolomic analysis revealed that female mussel Mytilus galloprovincialis was sensitive to bisphenol A exposures.ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,37(2),844-849.
MLA	Ji, Chenglong,et al."Metabolomic analysis revealed that female mussel Mytilus galloprovincialis was sensitive to bisphenol A exposures".ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 37.2(2014):844-849.