A novel fluorescent "turn-on" chemosensor for nanomolar detection of Fe(III) from aqueous solution and its application in living cells imaging

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 中科院海岸带环境过程与生态修复重点实验室

	A novel fluorescent "turn-on" chemosensor for nanomolar detection of Fe(III) from aqueous solution and its application in living cells imaging
	Nandre, Jitendra 1; Patil, Samadhan 1; Patil, Vijay 1; Yu, Fabiao 2; Chen, Lingxin2 ; Sahoo, Suban 3; Prior, Timothy 4; Redshaw, Carl 4; Mahulikar, Pramod 1; Patil, Umesh 1
刊名	BIOSENSORS & BIOELECTRONICS
	2014-11-15
卷号	61 页码:612-617
关键词	Fluorescent "turn-on" sensor Benzo-thiazolo-pyrimidine Fe3+ ICT PET Live cells imaging
ISSN号	0956-5663
通讯作者	Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Peoples R China. lxchen@yic.ac.cn ; mahulikarpp@rediffmail.com ; udpatil.nmu@gmail.com
产权排序	[Nandre, Jitendra; Patil, Samadhan; Patil, Vijay; Mahulikar, Pramod; Patil, Umesh] North Maharashtra Univ, Sch Chem Sci, Jalgaon 425001, MS, India; [Yu, Fabiao; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Peoples R China; [Sahoo, Suban] SV Natl Inst Technol, Dept Appl Chem, Surat 395007, Gujrat, India; [Prior, Timothy; Redshaw, Carl] Univ Hull, Dept Chem, Kingston Upon Hull HU6 7RX, N Humberside, England
中文摘要	An electronically active and spectral sensitive fluorescent "turn-on" chemosensor (BTP-1) based on the benzo-thiazolo-pyrimidine unit was designed and synthesized for the highly selective and sensitive detection of Fe3+ from aqueous medium. With Fe3+, the sensor BTP-1 showed a remarkable fluorescence enhancement at 554 nm (lambda(ex) = 314 nm) due to the inhibition of photo-induced electron transfer. The sensor formed a host-guest complex in 1:1 stoichiometry with the detection limit down to 0.74 nM. Further, the sensor was successfully utilized for the qualitative and quantitative intracellular detection of Fe3+ in two liver cell lines i.e., HepG2 cells (human hepatocellular liver carcinoma cell line) and HL-7701 cells (human normal liver cell line) by a confocal imaging technique. (C) 2014 Elsevier B.V. All rights reserved.
英文摘要	An electronically active and spectral sensitive fluorescent "turn-on" chemosensor (BTP-1) based on the benzo-thiazolo-pyrimidine unit was designed and synthesized for the highly selective and sensitive detection of Fe3+ from aqueous medium. With Fe3+, the sensor BTP-1 showed a remarkable fluorescence enhancement at 554 nm (lambda(ex) = 314 nm) due to the inhibition of photo-induced electron transfer. The sensor formed a host-guest complex in 1:1 stoichiometry with the detection limit down to 0.74 nM. Further, the sensor was successfully utilized for the qualitative and quantitative intracellular detection of Fe3+ in two liver cell lines i.e., HepG2 cells (human hepatocellular liver carcinoma cell line) and HL-7701 cells (human normal liver cell line) by a confocal imaging technique. (C) 2014 Elsevier B.V. All rights reserved.
学科主题	Biophysics; Biotechnology & Applied Microbiology; Chemistry, Analytical; Electrochemistry; Nanoscience & Nanotechnology
研究领域[WOS]	Biophysics ; Biotechnology & Applied Microbiology ; Chemistry ; Electrochemistry ; Science & Technology - Other Topics
关键词[WOS]	SENSORS ; POLYMER ; IONS ; FE3+
收录类别	SCI
语种	英语
WOS记录号	WOS:000339692500090
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/8693]
专题	烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
作者单位	1.North Maharashtra Univ, Sch Chem Sci, Jalgaon 425001, MS, India 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Peoples R China 3.SV Natl Inst Technol, Dept Appl Chem, Surat 395007, Gujrat, India 4.Univ Hull, Dept Chem, Kingston Upon Hull HU6 7RX, N Humberside, England
推荐引用方式 GB/T 7714	Nandre, Jitendra,Patil, Samadhan,Patil, Vijay,et al. A novel fluorescent "turn-on" chemosensor for nanomolar detection of Fe(III) from aqueous solution and its application in living cells imaging[J]. BIOSENSORS & BIOELECTRONICS,2014,61:612-617.
APA	Nandre, Jitendra.,Patil, Samadhan.,Patil, Vijay.,Yu, Fabiao.,Chen, Lingxin.,...&Patil, Umesh.(2014).A novel fluorescent "turn-on" chemosensor for nanomolar detection of Fe(III) from aqueous solution and its application in living cells imaging.BIOSENSORS & BIOELECTRONICS,61,612-617.
MLA	Nandre, Jitendra,et al."A novel fluorescent "turn-on" chemosensor for nanomolar detection of Fe(III) from aqueous solution and its application in living cells imaging".BIOSENSORS & BIOELECTRONICS 61(2014):612-617.