The assessment of plant metabolite profiles by NMR-based methodologies
Holmes, Elaine; Tang, Huiru; Wang, Yulan; Seger, Christoph
刊名PLANTA MEDICA
2006-07-01
卷号72期号:9页码:771-785
关键词NMR metabolic profiling metabolic fingerprinting metabolomics metabonomics phytomedicines traditional Chinese medicine genetically modified plants toxicology xenobiotics
英文摘要NMR-based metabolic profiling techniques can simultaneously track changes in many plant metabolites and have found a number of applications in both systems biology and biosafety. Together with multivariate statistical analyses, NMR spectroscopy has been successfully applied to the characterisation of various herbs and plant products for quality control, authentication, determining geographical origin and for detecting adulteration of products. Additionally, the metabolic consequences of plant extracts have been demonstrated in experimental animals and in man using NMR-based metabonomics approaches to characterise the response. Here the application of NMR spectroscopy and chemometric tools for analysing plant-based products and their metabolic consequences are considered with particular emphasis on deconvolving biological complexity and minimising confounding biological variability with analytical 'noise'.
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Plant Sciences ; Pharmacology & Pharmacy
关键词[WOS]NUCLEAR-MAGNETIC-RESONANCE ; VIRGIN OLIVE OILS ; MULTIVARIATE STATISTICAL-ANALYSIS ; PRINCIPAL COMPONENT ANALYSIS ; FIELD H-1-NMR SPECTROSCOPY ; NATURAL-PRODUCTS RESEARCH ; CHROMATOGRAPHY-MASS SPECTROMETRY ; MATRICARIA-RECUTITA L. ; JOHNS-WORT EXTRACTS ; HIGH-RESOLUTION NMR
收录类别SCI
语种英语
WOS记录号WOS:000239926000001
公开日期2015-07-28
内容类型期刊论文
源URL[http://ir.wipm.ac.cn/handle/112942/4650]  
专题武汉物理与数学研究所_2011年以前论文发表(包括2011年)
作者单位1.Univ Innsbruck, Ctr Mol Biosci, Inst Pharm Pharmacognosy, A-6020 Innsbruck, Austria
2.Univ London Imperial Coll Sci Technol & Med, Fac Nat Sci, Div Biomed Sci, London SW7 2AZ, England
3.Chinese Acad Sci, Wuhan Inst Phys & Math, Wuhan Magnet Resonance Ctr, State Key Lab Magnet Resonance & Mol & Atom Phys, Wuhan, Peoples R China
推荐引用方式
GB/T 7714
Holmes, Elaine,Tang, Huiru,Wang, Yulan,et al. The assessment of plant metabolite profiles by NMR-based methodologies[J]. PLANTA MEDICA,2006,72(9):771-785.
APA Holmes, Elaine,Tang, Huiru,Wang, Yulan,&Seger, Christoph.(2006).The assessment of plant metabolite profiles by NMR-based methodologies.PLANTA MEDICA,72(9),771-785.
MLA Holmes, Elaine,et al."The assessment of plant metabolite profiles by NMR-based methodologies".PLANTA MEDICA 72.9(2006):771-785.
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