Identification of Three Novel Polyphenolic Compounds, Origanine A-C, with Unique Skeleton from Origanum vulgare L. Using the Hyphenated LC-DAD-SPE-NMR/MS Methods

CORC > 武汉物理与数学研究所 > 中国科学院武汉物理与数学研究所 > 磁共振应用研究部

	Identification of Three Novel Polyphenolic Compounds, Origanine A-C, with Unique Skeleton from Origanum vulgare L. Using the Hyphenated LC-DAD-SPE-NMR/MS Methods
	Liu, Hongbing 1,4; Zheng, Anmin 1; Liu, Huili 1; Yu, Haiyan 1; Wu, Xiangyu 1,4; Xiao, Chaoni 1,2; Dai, Hui 1,3; Hao, Fuhua1 ; Zhang, Limin 1; Wang, Yulan 1
刊名	JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
	2012-01-11
卷号	60 期号:1 页码:129-135
关键词	Origanum vulgare L. polyphenolic compounds cyclohexenetetracarboxylic acids LC-DAD-SPE-NMR/MS origanine A-C computational calculations
英文摘要	Identification of new compounds especially those with new skeletons from plant kingdom has long been a vital aspect for understanding phytochemistry, plant metabolisms and discovering new bioactive compounds. In this study, we identified and isolated three novel polyphenolic compounds, origanine A-C, from a well-researched plant Origanum vulgare L. using the hyphenated LC-DAD-SPE-NMR/MS methods. Based on the combined information from UV-visible, accurate mass and 2D NMR spectra together with computational calculations, we found that these compounds all had a novel skeleton of cyclohexenetetracarboxylic acids attached with some well-known bioactive moieties including 3,4-dihydroxyphenyl, 4-(beta-D-glucopyranosyloxy)benzyl alcohol (gastrodin), and 3-(3,4-dihydroxyphenyl)lactic acid (danshensu) residues. These findings provided crucial information to fill the gaps in our knowledge in terms of the plant secondary metabolism. This study also indicated the necessity for further research in plant secondary metabolism for even well-studied plants and demonstrated the powerfulness of the hyphenated LC-DAD-SPE-NMR/MS methods for comprehensive analysis of plant metabolites in particular for discovering new natural compounds.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
类目[WOS]	Agriculture, Multidisciplinary ; Chemistry, Applied ; Food Science & Technology
研究领域[WOS]	Agriculture ; Chemistry ; Food Science & Technology
关键词[WOS]	ACID-DERIVATIVES ; GLUCOSIDE ; OREGANO ; PLANT
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000298943000020
公开日期	2015-07-14
内容类型	期刊论文
源URL	[http://ir.wipm.ac.cn/handle/112942/1673]
专题	武汉物理与数学研究所_磁共振应用研究部
作者单位	1.Chinese Acad Sci, Wuhan Inst Phys & Math, Wuhan Ctr Magnet Resonance, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan 430071, Peoples R China 2.NW Univ Xian, Coll Life Sci, Xian 710069, Peoples R China 3.Peking Univ, Dept Physiol & Pathophysiol, Beijing 100191, Peoples R China 4.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Liu, Hongbing,Zheng, Anmin,Liu, Huili,et al. Identification of Three Novel Polyphenolic Compounds, Origanine A-C, with Unique Skeleton from Origanum vulgare L. Using the Hyphenated LC-DAD-SPE-NMR/MS Methods[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2012,60(1):129-135.
APA	Liu, Hongbing.,Zheng, Anmin.,Liu, Huili.,Yu, Haiyan.,Wu, Xiangyu.,...&Tang, Huiru.(2012).Identification of Three Novel Polyphenolic Compounds, Origanine A-C, with Unique Skeleton from Origanum vulgare L. Using the Hyphenated LC-DAD-SPE-NMR/MS Methods.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,60(1),129-135.
MLA	Liu, Hongbing,et al."Identification of Three Novel Polyphenolic Compounds, Origanine A-C, with Unique Skeleton from Origanum vulgare L. Using the Hyphenated LC-DAD-SPE-NMR/MS Methods".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 60.1(2012):129-135.