A Selective NMR Method for Detecting Choline Containing Compounds in Liver Tissue: The H-1-N-14 HSQC Experiment
Mao, Jiezhen; Jiang, Ling; Jiang, Bin; Liu, Maili; Mao, Xi-an1
刊名JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2010-12-15
卷号132期号:49页码:17349-17351
产权排序第二
英文摘要The feasibility of a H-1-N-14 HSQC experiment on tissues is demonstrated with a mouse liver based on the J couplings between the protons and the quadrupolar nucleus N-14 in choline. Free choline, phosphocholine, and glycerolphosphocholine H-1-N-14 HSQC signals were selectively observed with all unwanted signals cleanly suppressed. The CH2O signals were well resolved in the two-dimensional spectrum, which can be used for quantitative analyses.
学科主题波谱分析
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]IN-VIVO ; CLINICAL-APPLICATIONS ; BREAST-CANCER ; SPECTROSCOPY ; METABOLISM ; THERAPY ; MRS
收录类别SCI
语种英语
WOS记录号WOS:000285328800005
内容类型期刊论文
源URL[http://ir.wipm.ac.cn/handle/112942/2095]  
专题武汉物理与数学研究所_2011年以前论文发表(包括2011年)
作者单位1.Case Western Reserve Univ, Sch Med, Dept Pharmacol, Cleveland, OH 44106 USA
2.Chinese Acad Sci, Wuhan Inst Phys & Math, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan 430071, Peoples R China
推荐引用方式
GB/T 7714
Mao, Jiezhen,Jiang, Ling,Jiang, Bin,et al. A Selective NMR Method for Detecting Choline Containing Compounds in Liver Tissue: The H-1-N-14 HSQC Experiment[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2010,132(49):17349-17351.
APA Mao, Jiezhen,Jiang, Ling,Jiang, Bin,Liu, Maili,&Mao, Xi-an.(2010).A Selective NMR Method for Detecting Choline Containing Compounds in Liver Tissue: The H-1-N-14 HSQC Experiment.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,132(49),17349-17351.
MLA Mao, Jiezhen,et al."A Selective NMR Method for Detecting Choline Containing Compounds in Liver Tissue: The H-1-N-14 HSQC Experiment".JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 132.49(2010):17349-17351.
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