Five new phenolic compounds from Dendrobium aphyllum
Yang, Dan1,2,4; Liu, Liang-Yan3; Cheng, Zhong-Quan4; Xu, Feng-Qing2; Fan, Wei-Wei2; Zi, Cheng-Ting1,2; Dong, Fa-Wu2; Zhou, Jun2; Ding, Zhong-Tao1; Hu, Jiang-Miao2
刊名FITOTERAPIA
2015
卷号100页码:11-18
关键词Dendrobium aphyllum Phenanthrene Bibenzyl derivative NO production
英文摘要One new phenanthrene, aphyllone A (1) and four new bibenzyl derivatives, aphyllone B (2) and aphyllals C-D (3-5), together with nine known compounds (6-14), were isolated from the stems of Dendrobium aphyllum (Roxb.) C. E. Fischer. The structures of these new compounds were elucidated by means of extensive spectroscopic analyses, and the absolute configuration of compound 1 was determined by single crystal X-ray diffraction and quantum calculations. Compounds 6,8 and 14 inhibited NO production at the concentration of 25 mu M in LPS-stimulated RAW264.7 cells with the inhibition (%) of 32.48, 35.68, and 38.50. Compound 2 possessed significant DPPH radical scavenging activity with scavenging percentage of 87.97% at the concentration of 100 mu g/mL. (C) 2014 Elsevier B.V. All rights reserved.
类目[WOS]Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]BIBENZYL DERIVATIVES ; CANDIDUM ; MOSCATUM
收录类别SCI
语种英语
WOS记录号WOS:000349881300003
公开日期2015-07-07
内容类型期刊论文
源URL[http://ir.kib.ac.cn/handle/151853/20429]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Yunnan Univ, Sch Chem Sci & Technol, Kunming 650091, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
3.Yunnan Agr Univ, Coll Agron & Biotechnol, Kunming 650201, Peoples R China
4.Guilin Normal Coll, Guilin 541001, Peoples R China
推荐引用方式
GB/T 7714
Yang, Dan,Liu, Liang-Yan,Cheng, Zhong-Quan,et al. Five new phenolic compounds from Dendrobium aphyllum[J]. FITOTERAPIA,2015,100:11-18.
APA Yang, Dan.,Liu, Liang-Yan.,Cheng, Zhong-Quan.,Xu, Feng-Qing.,Fan, Wei-Wei.,...&Hu, Jiang-Miao.(2015).Five new phenolic compounds from Dendrobium aphyllum.FITOTERAPIA,100,11-18.
MLA Yang, Dan,et al."Five new phenolic compounds from Dendrobium aphyllum".FITOTERAPIA 100(2015):11-18.
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