Repeated retrieval during working memory is sensitive to amnestic mild cognitive impairment

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	Repeated retrieval during working memory is sensitive to amnestic mild cognitive impairment
	Broster, Lucas S.; Li, Juan; Smith, Charles D.; Jicha, Gregory A.; Schmitt, Frederick A.; Jiang, Yang
刊名	JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY
	2013
卷号	35 期号:9 页码:946-959
关键词	Alzheimer disease Mild cognitive impairment Working memory Repetition priming Neuropsychological tests Cognitive therapy Aging
ISSN号	1537-4416
通讯作者	Jiang, Y (reprint author), Univ Kentucky, Coll Med, Dept Behav Sci, 113 Med Behav Sci Bldg, Lexington, KY 40536 USA.
产权排序	2
英文摘要	Study of repeated learning mechanisms has been limited in amnestic mild cognitive impairment, a preclinical stage of Alzheimer disease modifiable by cognitive rehabilitation. We assessed repeated contextual working memory decline as an indicator of amnestic mild cognitive impairment in a sample of 45 older adults recruited from the tertiary care setting. Results indicated that contextual working memory impairment distinguished adults with preclinical disease from those without impairment despite similar overall cognitive performance, and comparison of the indicator with standard-of-care neuropsychological measures indicated discriminant validity. Contextual working memory impairment may represent a novel predictor of Alzheimer disease conversion risk.
学科主题	Cognitive psychology
WOS标题词	Social Sciences ; Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Psychology, Clinical ; Clinical Neurology ; Psychology
研究领域[WOS]	Psychology ; Neurosciences & Neurology
关键词[WOS]	ALZHEIMERS ASSOCIATION WORKGROUPS ; INDEPENDENT COMPONENT ANALYSIS ; FREE-RECALL PERFORMANCE ; HEALTHY OLDER-ADULTS ; IMPLICIT MEMORY ; EPISODIC MEMORY ; SELECTIVE ATTENTION ; NEURAL MECHANISMS ; EXPLICIT MEMORY ; FUNCTIONAL CONNECTIVITY
收录类别	SCI
项目简介	This work was supported by funding from the Department of Energy [grant number DE-AC03-OR22725]; the National Institute of Health [grant number P50 AG05144-21], [grant number AG000986], [grant number 5P30AG028383], [grant number 5 T32 AG 242-18], [grant number UL1RR033173], [grant number UL1TR000117]; and a pilot grant from the University of Kentucky Department of Behavioral Science.
原文出处	http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884808/pdf/nihms529369.pdf
语种	英语
WOS记录号	WOS:000325959200006
内容类型	期刊论文
源URL	[http://ir.psych.ac.cn/handle/311026/10828]
专题	心理研究所_中国科学院心理健康重点实验室
作者单位	Jiang, Y (reprint author), Univ Kentucky, Coll Med, Dept Behav Sci, 113 Med Behav Sci Bldg, Lexington, KY 40536 USA.
推荐引用方式 GB/T 7714	Broster, Lucas S.,Li, Juan,Smith, Charles D.,et al. Repeated retrieval during working memory is sensitive to amnestic mild cognitive impairment[J]. JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY,2013,35(9):946-959.
APA	Broster, Lucas S.,Li, Juan,Smith, Charles D.,Jicha, Gregory A.,Schmitt, Frederick A.,&Jiang, Yang.(2013).Repeated retrieval during working memory is sensitive to amnestic mild cognitive impairment.JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY,35(9),946-959.
MLA	Broster, Lucas S.,et al."Repeated retrieval during working memory is sensitive to amnestic mild cognitive impairment".JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY 35.9(2013):946-959.