Differential gene expression in the respiratory tree of the sea cucumber Apostichopus japonicus during aestivation

CORC > 海洋研究所 > 中国科学院海洋研究所 > 海洋生态与环境科学重点实验室

	Differential gene expression in the respiratory tree of the sea cucumber Apostichopus japonicus during aestivation
	Zhao, Ye1,2 ; Yang, Hongsheng1 ; Storey, Kenneth B.3; Chen, Muyan 4
刊名	MARINE GENOMICS
	2014-12-01
卷号	18 页码:173-183
关键词	Apostichopus japonicus RNA-seq Respiratory tree Aestivation Differential gene expression
通讯作者	Yang, HS (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
英文摘要	Sea cucumbers, Apostichopus japonicus, experience seasonally high water temperatures during the summer months and enter aestivation to survive. Aestivation is characterized by strong metabolic rate depression which is supported by a series of strategies including reorganizing metabolic processes, suppressing cell functions, enhancing cytoprotective mechanisms, and altered gene expression. The respiratory tree tissue of the sea cucumber is an excellent material for studying aestivation, undergoing obvious atrophy during aestivation. The present study analyzed the global gene expression profile of respiratory tree tissue of A. japonicus during aestivation by constructing and screening three libraries representing key stages of aestivation: non-aestivation (NA), deep-aestivation (DA), and arousal from aestivation (M) using RNA-seq. A total of 1240, 1184 and 303 differentially expressed genes (DEGs) were identified following the criteria of [log(2) ratiol >= 1 and FDR <= 0.001 in comparisons of DA vs. NA, AA vs. NA and DA vs. AA. A set of respiratory tree specific DEGs was identified the first time and, in addition, common DEGs that were responsive to aestivation in both respiratory tree and intestine were identified. Functional analysis of DEGs was further performed by GO enrichment analysis and respiratory tree specific GO terms were screened out and provide interesting hints for further studies of the molecular regulation of aestivation in A. japonicus. (c) 2014 Elsevier B.V. All rights reserved.
学科主题	Genetics & Heredity; Marine & Freshwater Biology
收录类别	SCI
语种	英语
WOS记录号	WOS:000347578600024
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/24002]
专题	海洋研究所_海洋生态与环境科学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Carleton Univ, Inst Biochem, Ottawa, ON K1S 5B6, Canada 4.Ocean Univ China, Coll Fisheries, Qingdao 266003, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Ye,Yang, Hongsheng,Storey, Kenneth B.,et al. Differential gene expression in the respiratory tree of the sea cucumber Apostichopus japonicus during aestivation[J]. MARINE GENOMICS,2014,18:173-183.
APA	Zhao, Ye,Yang, Hongsheng,Storey, Kenneth B.,&Chen, Muyan.(2014).Differential gene expression in the respiratory tree of the sea cucumber Apostichopus japonicus during aestivation.MARINE GENOMICS,18,173-183.
MLA	Zhao, Ye,et al."Differential gene expression in the respiratory tree of the sea cucumber Apostichopus japonicus during aestivation".MARINE GENOMICS 18(2014):173-183.