Nanocomposite Incorporating V2O5 Nanowires and Gold Nanoparticles for Mimicking an Enzyme Cascade Reaction and Its Application in the Detection of Biomolecules

	Nanocomposite Incorporating V2O5 Nanowires and Gold Nanoparticles for Mimicking an Enzyme Cascade Reaction and Its Application in the Detection of Biomolecules
	Qu, Konggang ; Shi, Peng ; Ren, Jinsong ; Qu,Xiaogang
刊名	chemistry-a european journal
	2014
卷号	20 期号:24 页码:7501-7506
关键词	PEROXIDASE-LIKE ACTIVITY ARTIFICIAL ENZYMES CATALYTIC-ACTIVITY GRAPHENE OXIDE CHEMISTRY
通讯作者	qu,xg
英文摘要	artificial enzyme mimics are a current research interest, and many nanomaterials have been found to display enzyme-mimicking activity. however, to the best of our knowledge, there have not hitherto been any reports on the use of pure nanomaterials to construct a system capable of mimicking an enzyme cascade reaction. herein, we describe the construction of a novel nanocomposite consisting of v2o5 nanowires and gold nanoparticles (aunps) through a simple and facile chemical method, in which v2o5 and aunps possess intrinsic peroxidase and glucose oxidase (gox)-like activity, respectively. results suggest that this material can mimic the enzyme cascade reaction of horseradish peroxidase (hrp) and gox. based on this mechanism, a direct and selective colorimetric method for the detection of glucose has been successfully designed. because single-strand and double-strand dna (ssdna and dsdna) have different deactivating effects on the gox-like activity of aunps, the sensing of target complementary dna can also be realized and disease-associated single-nucleotide polymorphism of dna can be easily distinguished. our study opens a new avenue for the use of nanomaterials in enzyme mimetics, and holds promise for the further exploration of nanomaterials in creating alternative catalytic systems to natural enzymes.
收录类别	SCI
语种	英语
WOS记录号	WOS:000337617500039
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/52405]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Qu, Konggang,Shi, Peng,Ren, Jinsong,et al. Nanocomposite Incorporating V2O5 Nanowires and Gold Nanoparticles for Mimicking an Enzyme Cascade Reaction and Its Application in the Detection of Biomolecules[J]. chemistry-a european journal,2014,20(24):7501-7506.
APA	Qu, Konggang,Shi, Peng,Ren, Jinsong,&Qu,Xiaogang.(2014).Nanocomposite Incorporating V2O5 Nanowires and Gold Nanoparticles for Mimicking an Enzyme Cascade Reaction and Its Application in the Detection of Biomolecules.chemistry-a european journal,20(24),7501-7506.
MLA	Qu, Konggang,et al."Nanocomposite Incorporating V2O5 Nanowires and Gold Nanoparticles for Mimicking an Enzyme Cascade Reaction and Its Application in the Detection of Biomolecules".chemistry-a european journal 20.24(2014):7501-7506.