Applications of direct methods in protein crystallography for dealing with diffraction data down to 5 A resolution | |
Fan, HF ; Gu, YX ; He, Y ; Lin, ZJ ; Wang, JW ; Yao, DQ ; Zhang, T | |
刊名 | ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES |
2014 | |
卷号 | 70页码:239 |
ISSN号 | 0108-7673 |
通讯作者 | Fan, HF (reprint author), Chinese Acad Sci, Inst Phys, Beijing 100190, Peoples R China. |
中文摘要 | Apart from solving the heavy-atom substructure in proteins and ab initio phasing of protein diffraction data at atomic resolution, direct methods have also been successfully combined with other protein crystallographic methods in dealing with diffraction data far below atomic resolution, leading to significantly improved results. In this respect, direct methods provide phase constraints in reciprocal space within a dual-space iterative framework rather than solve the phase problem independently. Applications of this type of direct methods to difficult SAD phasing, model completion and low-resolution phase extension will be described in detail. (C) 2014 International Union of Crystallography |
资助信息 | Chinese Academy of Sciences; 973 Project of the Ministry of Science and Technology of China [2002CB713801] |
语种 | 英语 |
公开日期 | 2015-04-14 |
内容类型 | 期刊论文 |
源URL | [http://ir.iphy.ac.cn/handle/311004/58800] |
专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
推荐引用方式 GB/T 7714 | Fan, HF,Gu, YX,He, Y,et al. Applications of direct methods in protein crystallography for dealing with diffraction data down to 5 A resolution[J]. ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES,2014,70:239. |
APA | Fan, HF.,Gu, YX.,He, Y.,Lin, ZJ.,Wang, JW.,...&Zhang, T.(2014).Applications of direct methods in protein crystallography for dealing with diffraction data down to 5 A resolution.ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES,70,239. |
MLA | Fan, HF,et al."Applications of direct methods in protein crystallography for dealing with diffraction data down to 5 A resolution".ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 70(2014):239. |
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