Femtosecond Transient Absorption Spectroscopy Study of the Early Events of Norfloxacin in Aqueous Solutions with Varying pH Values

CORC > 上海应用物理研究所 > 中国科学院上海应用物理研究所 > 中科院上海应用物理研究所2011-2017年

	Femtosecond Transient Absorption Spectroscopy Study of the Early Events of Norfloxacin in Aqueous Solutions with Varying pH Values
	Su, T ; Li, MD ; Ma, JN ; Wong, NK ; Phillips, DL
刊名	JOURNAL OF PHYSICAL CHEMISTRY B
	2014
卷号	118 期号:47 页码:13458—13467
关键词	FLUOROQUINOLONE ANTIBIOTICS STEADY-STATE COMET ASSAY PHOTOCHEMISTRY MEDIA PHOTOSENSITIZATION PHOTOREACTIVITY LOMEFLOXACIN NANOSECOND BEHAVIOR
ISSN号	1520-6106
通讯作者	mdli@huk.hk ; phillips@hku.hk
英文摘要	The photophysics and photochemistry of norfloxacin (NF) have been investigated in aqueous solutions of different pH using femtosecond transient absorption spectroscopy (fs-TA). Resonance Raman spectroscopic experiments on NF have also been conducted in aqueous solutions of different pH to characterize the vibrational and structural information on the initial forms of NF. The experimental results in combination with density functional theory calculations of the key intermediates help us to elucidate the early events for NF after photoexcitation in aqueous solutions with varying pH values. The fs-TA results indicate that NF mainly underwent photophysical processes on the early delay time scale (before 3 ns), and no photochemical reactions occurred on this time scale. Specifically, after the irradiation of NF, the molecule reaches a higher excited singlet S-n and then decays to the lowest-lying excited singlet state S-1 followed by intersystem crossing to transform into the lowest-lying triplet state T-1 with a high efficiency, with an exception that there is a lower efficiency observed in basic aqueous solution due to the generation of an intramolecular electron transfer as an additional pathway to waste energy.
收录类别	SCI
语种	英语
WOS记录号	WOS:000345722900020
公开日期	2015-03-13
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/14138]
专题	上海应用物理研究所_中科院上海应用物理研究所2011-2017年
推荐引用方式 GB/T 7714	Su, T,Li, MD,Ma, JN,et al. Femtosecond Transient Absorption Spectroscopy Study of the Early Events of Norfloxacin in Aqueous Solutions with Varying pH Values[J]. JOURNAL OF PHYSICAL CHEMISTRY B,2014,118(47):13458—13467.
APA	Su, T,Li, MD,Ma, JN,Wong, NK,&Phillips, DL.(2014).Femtosecond Transient Absorption Spectroscopy Study of the Early Events of Norfloxacin in Aqueous Solutions with Varying pH Values.JOURNAL OF PHYSICAL CHEMISTRY B,118(47),13458—13467.
MLA	Su, T,et al."Femtosecond Transient Absorption Spectroscopy Study of the Early Events of Norfloxacin in Aqueous Solutions with Varying pH Values".JOURNAL OF PHYSICAL CHEMISTRY B 118.47(2014):13458—13467.