Anti-inflammatory activity of Jatropha curcas roots in mice and rats

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	Anti-inflammatory activity of Jatropha curcas roots in mice and rats
	Mujumdar, A. M.
刊名	Journal of Ethnopharmacology
	2004
卷号	90 期号:1 页码:42323
ISSN号	0378-8741
中文摘要	Anti-inflammatory activity of topical application of Jatropha curcas L. root powder in paste form in TPA-induced ear inflammation was confirmed in albino mice and the successive solvent extraction of these roots was carried out by ether and methanol. The methanol extract exhibited systemic and significant anti-inflammatory activity in acute carrageenan-induced rat paw. edema. It also showed activity against formalin-induced rat paw edema, as well as, turpentine-induced exudative changes and cotton pellet-induced granular tissue formation after oral treatment for 7 days in albino rats. Thus, resultant anti-inflammatory activity might be due to effects on several mediators and arachidonic acid metabolism involving cyclo-oxygenase pathway resulting in prostaglandin formation, anti-proliferative activity leading to reduction in granular tissue formation and leukocyte migration from the vessels. (C) 2003 Published by Elsevier Ireland Ltd.
公开日期	2015-01-28
内容类型	期刊论文
源URL	[http://ir.xtbg.org.cn/handle/353005/7315]
专题	西双版纳热带植物园_热带植物资源可持续利用重点实验室特色文献_小桐子相关文献
推荐引用方式 GB/T 7714	Mujumdar, A. M.. Anti-inflammatory activity of Jatropha curcas roots in mice and rats[J]. Journal of Ethnopharmacology,2004,90(1):42323.
APA	Mujumdar, A. M..(2004).Anti-inflammatory activity of Jatropha curcas roots in mice and rats.Journal of Ethnopharmacology,90(1),42323.
MLA	Mujumdar, A. M.."Anti-inflammatory activity of Jatropha curcas roots in mice and rats".Journal of Ethnopharmacology 90.1(2004):42323.