Pegaharmalines A and B, two novel beta-carboline alkaloids with unprecedented carbon skeletons from Peganum harmala

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	Pegaharmalines A and B, two novel beta-carboline alkaloids with unprecedented carbon skeletons from Peganum harmala
	Wang, Kai-Bo 1; Yuan, Chun-Mao 2; Xue, Chun-Mei 1; Li, Da-Hong 1; Jing, Yong-Kui 3; He, Hong-Ping 2; Hao, Xiao-Jiang2 ; Di, Ying-Tong2 ; Li, Zhan-Lin 1; Hua, Hui-Ming 1
刊名	RSC ADVANCES
	2014
卷号	4 期号:96 页码:53725-53729
关键词	LIVERWORT LEPIDOLAENA-CLAVIGERA CASPASE-3 INHIBITORY-ACTIVITY SP NO 27 ABSOLUTE-CONFIGURATION ASPERGILLUS-FUMIGATUS TETRACYCLIC SKELETON CHAETOMIUM-ELATUM PHIALOPHORA METABOLITES ACETALS
ISSN号	2046-2069
通讯作者	Hua,HM (reprint author),Shenyang Pharmaceut Univ,Key Lab Struct Based Drug Design & Discovery,Minist Educ,Shenyang 110016,Peoples R China.
产权排序	第二
英文摘要	Pegaharmalines A (1) and B (2), two novel beta-carboline alkaloids with unprecedented carbon skeletons, were isolated from the seeds of Peganum harmala. Their structures were determined by spectroscopic methods and the absolute configuration of 1 was elucidated by CD analysis. 1 and 2 exhibited significant cytotoxicities on HL-60 cells with IC50 values of 9.4 and 13.6 mu M, respectively.
学科主题	Chemistry, Multidisciplinary
类目[WOS]	Chemistry, Multidisciplinary
研究领域[WOS]	Chemistry
关键词[WOS]	SCAFFOLD ; ROOTS ; MODES
收录类别	SCI
语种	英语
WOS记录号	WOS:000344468800043
公开日期	2015-01-20
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/18484]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Shenyang Pharmaceut Univ, Key Lab Struct Based Drug Design & Discovery, Minist Educ, Shenyang 110016, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 3.Mt Sinai Sch Med, Dept Med, New York, NY 10029 USA
推荐引用方式 GB/T 7714	Wang, Kai-Bo,Yuan, Chun-Mao,Xue, Chun-Mei,et al. Pegaharmalines A and B, two novel beta-carboline alkaloids with unprecedented carbon skeletons from Peganum harmala[J]. RSC ADVANCES,2014,4(96):53725-53729.
APA	Wang, Kai-Bo.,Yuan, Chun-Mao.,Xue, Chun-Mei.,Li, Da-Hong.,Jing, Yong-Kui.,...&Hua, Hui-Ming.(2014).Pegaharmalines A and B, two novel beta-carboline alkaloids with unprecedented carbon skeletons from Peganum harmala.RSC ADVANCES,4(96),53725-53729.
MLA	Wang, Kai-Bo,et al."Pegaharmalines A and B, two novel beta-carboline alkaloids with unprecedented carbon skeletons from Peganum harmala".RSC ADVANCES 4.96(2014):53725-53729.