Superhydrophobic Gated Polyorganosilanes/Halloysite Nanocontainers for Sustained Drug Release | |
Fan L(范玲); Li BC(李步成); Wang Q(汪琴); Wang AQ(王爱勤); Zhang JP(张俊平); Zhang JP(张俊平) | |
刊名 | Advanced Materials Interfaces |
2014 | |
卷号 | 1期号:5页码:1300136(1-7) |
ISSN号 | 2196-7350 |
通讯作者 | 张俊平 |
英文摘要 | Inspired by the water repellency of the lotus leaf, superhydrophobic gated nanocontainers are fabricated by using halloysite nanotubes (HNTs) as the nanocontainers and polyorganosilanes (POS) as the molecular gates for sustained release of diclofenac sodium (DS). The nanocontainers are prepared by loading DS into the lumen of HNTs, and then modified by co-condensation of hexadecyltriethoxylsilane and tetraethoxysilane. The nanocontainers are characterized with transmission electron microscopy, energy dispersive X-ray analysis and FTIR, etc. The wetting behaviors of the nanocontainers and release behaviors of DS are also studied. DS molecules are loaded in the lumen of HNTs and POS is covalently bonded on the surface of HNTs-DS. Wettability of the nanocontainers is controllable simply by the POS content. The nanocontainers show excellent superhydrophobicity with a water contact angle of 156.9° and a water shedding angle of 3°. The release of DS molecules is controlled by a new way, the air cushion between the superhydrophobic nanocontainers and the phosphate buffer solution (PBS). The DS molecules could only release from the limited place where the nanocontainers contact with PBS when the PBS is in the Cassie-Baxter state on the surface of the nanocontainers. |
学科主题 | 环境材料与生态化学 |
收录类别 | SCI |
资助信息 | the National Natural Science Foundation of China (No.51003112);the “Hundred Talents Program” of the Chinese Academy of Sciences |
语种 | 英语 |
WOS记录号 | WOS:000348283700007 |
公开日期 | 2014-12-08 |
内容类型 | 期刊论文 |
源URL | [http://210.77.64.217/handle/362003/6870] |
专题 | 兰州化学物理研究所_环境材料与生态化学研究发展中心 |
通讯作者 | Zhang JP(张俊平) |
作者单位 | Chinese Acad Sci, Lanzhou Inst Chem Phys, Ctr Ecomat & Green Chem, Lanzhou 730000, Peoples R China |
推荐引用方式 GB/T 7714 | Fan L,Li BC,Wang Q,et al. Superhydrophobic Gated Polyorganosilanes/Halloysite Nanocontainers for Sustained Drug Release[J]. Advanced Materials Interfaces,2014,1(5):1300136(1-7). |
APA | Fan L,Li BC,Wang Q,Wang AQ,Zhang JP,&张俊平.(2014).Superhydrophobic Gated Polyorganosilanes/Halloysite Nanocontainers for Sustained Drug Release.Advanced Materials Interfaces,1(5),1300136(1-7). |
MLA | Fan L,et al."Superhydrophobic Gated Polyorganosilanes/Halloysite Nanocontainers for Sustained Drug Release".Advanced Materials Interfaces 1.5(2014):1300136(1-7). |
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