Three new polyketides from marine-derived fungus Penicillium citrinum SCSGAF 0167

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	Three new polyketides from marine-derived fungus Penicillium citrinum SCSGAF 0167
	Sun, YL ; Zhang, XY ; Zheng, ZH ; Xu, XY ; Qi, SH
刊名	NATURAL PRODUCT RESEARCH
	2014
卷号	28 期号:4 页码:239-244
关键词	Penicillium citrinum polyketide cathepsin B inhibitor
ISSN号	1478-6419
通讯作者	shuhuaqi@scsio.ac.cn
中文摘要	Three new polyketides penicitrinol G (1), penicitrinol H (2) and 2,11-dihydroxy-1-methoxycarbonyl-9-carboxylxanthone (3) together with one known cathepsin B inhibitor chrysophanol (4) were isolated from a culture broth of marine-derived fungus Penicillium citrinum SCSGAF 0167. Their structures were determined by spectroscopic methods. Compound 4 exhibited inhibitory activity against cathepsin B with IC50 value of 1.7 mu M.
学科主题	Chemistry ; Pharmacology & Pharmacy
收录类别	SCI
资助信息	973 Program of China [2010CB833803]; 863 Program of China [2012AA092104]; National Marine Public Welfare Research Project of China [201305017]; National Natural Science Foundation of China [40931160435, 40976090]; Science and Technology Foundation of Guangdong Province [2010B030600009]
原文出处	TAYLOR & FRANCIS LTD
WOS记录号	WOS:000333939500004
公开日期	2014-12-11
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/10470]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
推荐引用方式 GB/T 7714	Sun, YL,Zhang, XY,Zheng, ZH,et al. Three new polyketides from marine-derived fungus Penicillium citrinum SCSGAF 0167[J]. NATURAL PRODUCT RESEARCH,2014,28(4):239-244.
APA	Sun, YL,Zhang, XY,Zheng, ZH,Xu, XY,&Qi, SH.(2014).Three new polyketides from marine-derived fungus Penicillium citrinum SCSGAF 0167.NATURAL PRODUCT RESEARCH,28(4),239-244.
MLA	Sun, YL,et al."Three new polyketides from marine-derived fungus Penicillium citrinum SCSGAF 0167".NATURAL PRODUCT RESEARCH 28.4(2014):239-244.