De Novo Design, Synthesis and Evaluation of Benzylpiperazine Derivatives as Highly Selective Binders of Mcl-1

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	De Novo Design, Synthesis and Evaluation of Benzylpiperazine Derivatives as Highly Selective Binders of Mcl-1
	Ding X(丁晓) ; Li Y(李嫣) ; Lv L(吕丽) ; Zhou M(周宓) ; Han L(韩莉) ; Zhang ZX(张政希) ; Li JQ(李井泉) ; Wang H(王辉) ; Liu H(柳红) ; Wang RX(王任小)
刊名	ChemMedChem
	2013
卷号	8 期号:12 页码:1986-2014
ISSN号	1860-7179
其他题名	从头设计, 合成和评价高选择性Mcl-1抑制剂苄基哌嗪类衍生物
通讯作者	柳红 ; 王任小
英文摘要	Considerable efforts have been made to the development of small-molecule inhibitors of antiapoptotic B-cell lymphoma2 (Bcl-2) family proteins (such as Bcl-2, Bcl-x(L), and Mcl-1) as a new class of anticancer therapies. Unlike general inhibitors of the ent
学科主题	有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1002/cmdc.201300316
语种	英语
WOS记录号	WOS:000327504400009
公开日期	2014-12-08
内容类型	期刊论文
源URL	[http://ir.sioc.ac.cn/handle/331003/29463]
专题	上海有机化学研究所_计算机化学与化学信息学研究室
推荐引用方式 GB/T 7714	Ding X,Li Y,Lv L,et al. De Novo Design, Synthesis and Evaluation of Benzylpiperazine Derivatives as Highly Selective Binders of Mcl-1[J]. ChemMedChem,2013,8(12):1986-2014.
APA	丁晓.,李嫣.,吕丽.,周宓.,韩莉.,...&王任小.(2013).De Novo Design, Synthesis and Evaluation of Benzylpiperazine Derivatives as Highly Selective Binders of Mcl-1.ChemMedChem,8(12),1986-2014.
MLA	丁晓,et al."De Novo Design, Synthesis and Evaluation of Benzylpiperazine Derivatives as Highly Selective Binders of Mcl-1".ChemMedChem 8.12(2013):1986-2014.