Click aspartic acid as H ILIC SPE material for selective enrichment of N-linked glycopeptides

	Click aspartic acid as H ILIC SPE material for selective enrichment of N-linked glycopeptides
	Li, Xiuling 1; Shen, Guobin 2; Zhang, FeiFang 2; Yang, Bingcheng 2; Liang, Xinmiao 1,2
刊名	journal of chromatography b-analytical technologies in the biomedical and life sciences
	2013-12-15
卷号	941 页码:45-49
关键词	Glycopeptides Hydrophilic interaction chromatography Aspartic acid Click chemistry Solid phase extraction
通讯作者	5
产权排序	待补充
合作状况	英
英文摘要	a novel hydrophilic interaction chromatography (hilic) material was developed via clicking aspartic acid onto silica gel (termed as click aa). the material demonstrated highly hydrophilic property and was used as solid phase extraction sorbent for selective enrichment of glycopeptides. by optimization of extraction conditions, click aa exhibited high selectivity to glycopeptides with various peptide length and different types of glycans, which was much superior to similar commercial products. the application of click aa to simulated proteomic samples further proved its specialty toward glycopeptides. (c) 2013 elsevier b.v. all rights reserved.
学科主题	物理化学
WOS标题词	science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]	biochemical research methods ; chemistry, analytical
研究领域[WOS]	biochemistry & molecular biology ; chemistry
关键词[WOS]	interaction liquid-chromatography ; titanium-dioxide chromatography ; mass-spectrometry ; glycosylation ; phase ; matrix ; glycoproteomics ; identification ; fractionation ; separation
收录类别	SCI
资助信息	1，1
原文出处	49
语种	英语
WOS记录号	WOS:000327367100007
公开日期	2014-09-11
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/119617]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Key Lab Separat Sci Analyt Chem, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China
推荐引用方式 GB/T 7714	Li, Xiuling,Shen, Guobin,Zhang, FeiFang,et al. Click aspartic acid as H ILIC SPE material for selective enrichment of N-linked glycopeptides[J]. journal of chromatography b-analytical technologies in the biomedical and life sciences,2013,941:45-49.
APA	Li, Xiuling,Shen, Guobin,Zhang, FeiFang,Yang, Bingcheng,&Liang, Xinmiao.(2013).Click aspartic acid as H ILIC SPE material for selective enrichment of N-linked glycopeptides.journal of chromatography b-analytical technologies in the biomedical and life sciences,941,45-49.
MLA	Li, Xiuling,et al."Click aspartic acid as H ILIC SPE material for selective enrichment of N-linked glycopeptides".journal of chromatography b-analytical technologies in the biomedical and life sciences 941(2013):45-49.