Biosafe Nanoscale Pharmaceutical Adjuvant Materials

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	Biosafe Nanoscale Pharmaceutical Adjuvant Materials
	Jin, Shubin 1; Li, Shengliang 1,2; Wang, Chongxi 1; Liu, Juan 1; Yang, Xiaolong 1; Wang, Paul C.3; Zhang, Xin 4; Liang, Xing-Jie 1
刊名	JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
	2014-09-01
卷号	10 期号:9 页码:2393-2419
关键词	Drug Delivery Adjuvant Nanomaterials Biosafe Multifunction Nanoparticle Controlled Release
ISSN号	1550-7033
其他题名	J. Biomed. Nanotechnol.
中文摘要	Thanks to developments in the field of nanotechnology over the past decades, more and more biosafe nanoscale materials have become available for use as pharmaceutical adjuvants in medical research. Nanomaterials possess unique properties which could be employed to develop drug carriers with longer circulation time, higher loading capacity, better stability in physiological conditions, controlled drug release, and targeted drug delivery. In this review article, we will review recent progress in the application of representative organic, inorganic and hybrid biosafe nanoscale materials in pharmaceutical research, especially focusing on nanomaterial-based novel drug delivery systems. In addition, we briefly discuss the advantages and notable functions that make these nanomaterials suitable for the design of new medicines; the biosafety of each material discussed in this article is also highlighted to provide a comprehensive understanding of their adjuvant attributes.
英文摘要	Thanks to developments in the field of nanotechnology over the past decades, more and more biosafe nanoscale materials have become available for use as pharmaceutical adjuvants in medical research. Nanomaterials possess unique properties which could be employed to develop drug carriers with longer circulation time, higher loading capacity, better stability in physiological conditions, controlled drug release, and targeted drug delivery. In this review article, we will review recent progress in the application of representative organic, inorganic and hybrid biosafe nanoscale materials in pharmaceutical research, especially focusing on nanomaterial-based novel drug delivery systems. In addition, we briefly discuss the advantages and notable functions that make these nanomaterials suitable for the design of new medicines; the biosafety of each material discussed in this article is also highlighted to provide a comprehensive understanding of their adjuvant attributes.
WOS标题词	Science & Technology ; Technology
类目[WOS]	Nanoscience & Nanotechnology ; Materials Science, Biomaterials
研究领域[WOS]	Science & Technology - Other Topics ; Materials Science
关键词[WOS]	MESOPOROUS SILICA NANOPARTICLES ; TARGETED DRUG-DELIVERY ; GLYCOL CHITOSAN NANOPARTICLES ; RESPONSIVE CONTROLLED-RELEASE ; SIZE-DEPENDENT CYTOTOXICITY ; CELL-PENETRATING PEPTIDES ; CORE-SHELL NANOPARTICLES ; IRON-OXIDE NANOPARTICLES ; WATER-SOLUBLE CHITOSAN ; GROWTH-FACTOR RECEPTOR
收录类别	SCI
原文出处	://WOS:000339430600031
语种	英语
WOS记录号	WOS:000339430600031
公开日期	2014-08-29
内容类型	期刊论文
版本	出版稿
源URL	[http://ir.ipe.ac.cn/handle/122111/11334]
专题	过程工程研究所_研究所（批量导入）
作者单位	1.Natl Ctr Nanosci & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China 2.Sun Yat Sen Univ, Zhongshan Sch Med, Dept Neurobiol & Anat, Guangzhou 510275, Guangdong, Peoples R China 3.Howard Univ, Dept Radiol, Lab Mol Imaging, Washington, DC 20060 USA 4.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Jin, Shubin,Li, Shengliang,Wang, Chongxi,et al. Biosafe Nanoscale Pharmaceutical Adjuvant Materials[J]. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,2014,10(9):2393-2419.
APA	Jin, Shubin.,Li, Shengliang.,Wang, Chongxi.,Liu, Juan.,Yang, Xiaolong.,...&Liang, Xing-Jie.(2014).Biosafe Nanoscale Pharmaceutical Adjuvant Materials.JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,10(9),2393-2419.
MLA	Jin, Shubin,et al."Biosafe Nanoscale Pharmaceutical Adjuvant Materials".JOURNAL OF BIOMEDICAL NANOTECHNOLOGY 10.9(2014):2393-2419.