Biosafe Nanoscale Pharmaceutical Adjuvant Materials | |
Jin, Shubin1; Li, Shengliang1,2; Wang, Chongxi1; Liu, Juan1; Yang, Xiaolong1; Wang, Paul C.3; Zhang, Xin4; Liang, Xing-Jie1 | |
刊名 | JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
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2014-09-01 | |
卷号 | 10期号:9页码:2393-2419 |
关键词 | Drug Delivery Adjuvant Nanomaterials Biosafe Multifunction Nanoparticle Controlled Release |
ISSN号 | 1550-7033 |
其他题名 | J. Biomed. Nanotechnol. |
中文摘要 | Thanks to developments in the field of nanotechnology over the past decades, more and more biosafe nanoscale materials have become available for use as pharmaceutical adjuvants in medical research. Nanomaterials possess unique properties which could be employed to develop drug carriers with longer circulation time, higher loading capacity, better stability in physiological conditions, controlled drug release, and targeted drug delivery. In this review article, we will review recent progress in the application of representative organic, inorganic and hybrid biosafe nanoscale materials in pharmaceutical research, especially focusing on nanomaterial-based novel drug delivery systems. In addition, we briefly discuss the advantages and notable functions that make these nanomaterials suitable for the design of new medicines; the biosafety of each material discussed in this article is also highlighted to provide a comprehensive understanding of their adjuvant attributes. |
英文摘要 | Thanks to developments in the field of nanotechnology over the past decades, more and more biosafe nanoscale materials have become available for use as pharmaceutical adjuvants in medical research. Nanomaterials possess unique properties which could be employed to develop drug carriers with longer circulation time, higher loading capacity, better stability in physiological conditions, controlled drug release, and targeted drug delivery. In this review article, we will review recent progress in the application of representative organic, inorganic and hybrid biosafe nanoscale materials in pharmaceutical research, especially focusing on nanomaterial-based novel drug delivery systems. In addition, we briefly discuss the advantages and notable functions that make these nanomaterials suitable for the design of new medicines; the biosafety of each material discussed in this article is also highlighted to provide a comprehensive understanding of their adjuvant attributes. |
WOS标题词 | Science & Technology ; Technology |
类目[WOS] | Nanoscience & Nanotechnology ; Materials Science, Biomaterials |
研究领域[WOS] | Science & Technology - Other Topics ; Materials Science |
关键词[WOS] | MESOPOROUS SILICA NANOPARTICLES ; TARGETED DRUG-DELIVERY ; GLYCOL CHITOSAN NANOPARTICLES ; RESPONSIVE CONTROLLED-RELEASE ; SIZE-DEPENDENT CYTOTOXICITY ; CELL-PENETRATING PEPTIDES ; CORE-SHELL NANOPARTICLES ; IRON-OXIDE NANOPARTICLES ; WATER-SOLUBLE CHITOSAN ; GROWTH-FACTOR RECEPTOR |
收录类别 | SCI |
原文出处 | |
语种 | 英语 |
WOS记录号 | WOS:000339430600031 |
公开日期 | 2014-08-29 |
内容类型 | 期刊论文 |
版本 | 出版稿 |
源URL | [http://ir.ipe.ac.cn/handle/122111/11334] ![]() |
专题 | 过程工程研究所_研究所(批量导入) |
作者单位 | 1.Natl Ctr Nanosci & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China 2.Sun Yat Sen Univ, Zhongshan Sch Med, Dept Neurobiol & Anat, Guangzhou 510275, Guangdong, Peoples R China 3.Howard Univ, Dept Radiol, Lab Mol Imaging, Washington, DC 20060 USA 4.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Jin, Shubin,Li, Shengliang,Wang, Chongxi,et al. Biosafe Nanoscale Pharmaceutical Adjuvant Materials[J]. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,2014,10(9):2393-2419. |
APA | Jin, Shubin.,Li, Shengliang.,Wang, Chongxi.,Liu, Juan.,Yang, Xiaolong.,...&Liang, Xing-Jie.(2014).Biosafe Nanoscale Pharmaceutical Adjuvant Materials.JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,10(9),2393-2419. |
MLA | Jin, Shubin,et al."Biosafe Nanoscale Pharmaceutical Adjuvant Materials".JOURNAL OF BIOMEDICAL NANOTECHNOLOGY 10.9(2014):2393-2419. |
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