The antioxidant activities and neuroprotective effect of polysaccharides from the starfish Asterias rollestoni

	The antioxidant activities and neuroprotective effect of polysaccharides from the starfish Asterias rollestoni
	Zhang, Wenjing1,2,3 ; Wang, Jing1,3 ; Jin, Weihua 1,2; Zhang, Quanbin 1
刊名	CARBOHYDRATE POLYMERS
	2013-05-05
卷号	95 期号:1 页码:9-15
关键词	Starfish Polysaccharide Antioxidant activity Neuroprotective activity
ISSN号	0144-8617
通讯作者	Zhang, QB
中文摘要	After the starfish was defatted with isopropyl alcohol and ethanol, crude polysaccharide was extracted by 0.15 mol/L NCl. Anion exchange chromatography was performed to fractionate the sample into two fractions, SF-1 and SF-2. Chemical analysis showed that the major component of SF-1 was a glucan consisting of a backbone of 1 -> 3 linked beta-D-glucopyranose residues, and it had a minor glucan component containing a backbone of 1 -> 3 linked alpha-D-glucopyranose residues. SF-2 was a mannoglucan sulfate. SF-2 displayed the highest antioxidant activity among the polysaccharides. Moreover, SF-1 and SF-2 exhibited neuroprotective activities in a neurotoxicity model of Parkinson's disease (PD). (C) 2013 Elsevier Ltd. All rights reserved.
英文摘要	After the starfish was defatted with isopropyl alcohol and ethanol, crude polysaccharide was extracted by 0.15 mol/L NCl. Anion exchange chromatography was performed to fractionate the sample into two fractions, SF-1 and SF-2. Chemical analysis showed that the major component of SF-1 was a glucan consisting of a backbone of 1 -> 3 linked beta-D-glucopyranose residues, and it had a minor glucan component containing a backbone of 1 -> 3 linked alpha-D-glucopyranose residues. SF-2 was a mannoglucan sulfate. SF-2 displayed the highest antioxidant activity among the polysaccharides. Moreover, SF-1 and SF-2 exhibited neuroprotective activities in a neurotoxicity model of Parkinson's disease (PD). (C) 2013 Elsevier Ltd. All rights reserved.
学科主题	Chemistry ; Polymer Science
WOS标题词	Science & Technology ; Physical Sciences
类目[WOS]	Chemistry, Applied ; Chemistry, Organic ; Polymer Science
研究领域[WOS]	Chemistry ; Polymer Science
关键词[WOS]	POLYHYDROXYLATED STEROIDS ; SULFATED POLYSACCHARIDES ; MARINE-INVERTEBRATES ; ANTICOAGULANT ; FRACTIONS ; EXTRACTS
收录类别	SCI
原文出处	10.1016/j.carbpol.2013.02.035
语种	英语
WOS记录号	WOS:000319029700002
公开日期	2014-07-17
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/16725]
专题	海洋研究所_海洋生物技术研发中心
作者单位	1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.IOCAS Jiangsu, Nantong Marine Sci & Technol R&D Ctr, Nantong 226006, Jiangsu, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Wenjing,Wang, Jing,Jin, Weihua,et al. The antioxidant activities and neuroprotective effect of polysaccharides from the starfish Asterias rollestoni[J]. CARBOHYDRATE POLYMERS,2013,95(1):9-15.
APA	Zhang, Wenjing,Wang, Jing,Jin, Weihua,&Zhang, Quanbin.(2013).The antioxidant activities and neuroprotective effect of polysaccharides from the starfish Asterias rollestoni.CARBOHYDRATE POLYMERS,95(1),9-15.
MLA	Zhang, Wenjing,et al."The antioxidant activities and neuroprotective effect of polysaccharides from the starfish Asterias rollestoni".CARBOHYDRATE POLYMERS 95.1(2013):9-15.