Biological and chemical diversity of cytotoxin-producing symbiotic marine fungi in intertidal zone of Dalian

CORC > 海洋研究所 > 中国科学院海洋研究所 > 实验海洋生物学重点实验室

	Biological and chemical diversity of cytotoxin-producing symbiotic marine fungi in intertidal zone of Dalian
	Zhang Yi 1,2,3; Mu Jun 2; Feng Yan 2; Li HeNan 2; Dong XueWei 2; Zhang, Y
刊名	CHINESE SCIENCE BULLETIN
	2013-07-01
卷号	58 期号:19 页码:2290-2297
关键词	symbiotic marine fungi cytotoxicity diversity rDNA sequencing morphology fingerprint
ISSN号	1001-6538
通讯作者	Zhang, Y
中文摘要	In this study, the biological and chemical diversity of 8 symbiotic marine fungal strains, with strong cytotoxicity against brine shrimp larvae, were investigated by nucleotide sequencing, morphology and cluster analysis of HPTLC fingerprint. These strains were identified by ITS rDNA sequencing, phylogenic analysis, and morphology to be Hypocrea lixii, Chaetomium globosum, Aspergillus fumigatus, Asp. clavatus and Alternaria sp. Their differences in secondary metabolites were shown by cluster analysis of digitalized colors of HPTLC spots, a newly developed method, which produced a similar dendrogram with that of ITS cluster analysis. Furthermore, this method can fully display intraspecific differences and even the remarkable difference in Aspergillus strains which goes beyond the boundary between genera. Their biological-chemical diversity may be the basis of their potent cytotoxicity and implies their potential in producing diversified antitumor or pesticidal constituents.
英文摘要	In this study, the biological and chemical diversity of 8 symbiotic marine fungal strains, with strong cytotoxicity against brine shrimp larvae, were investigated by nucleotide sequencing, morphology and cluster analysis of HPTLC fingerprint. These strains were identified by ITS rDNA sequencing, phylogenic analysis, and morphology to be Hypocrea lixii, Chaetomium globosum, Aspergillus fumigatus, Asp. clavatus and Alternaria sp. Their differences in secondary metabolites were shown by cluster analysis of digitalized colors of HPTLC spots, a newly developed method, which produced a similar dendrogram with that of ITS cluster analysis. Furthermore, this method can fully display intraspecific differences and even the remarkable difference in Aspergillus strains which goes beyond the boundary between genera. Their biological-chemical diversity may be the basis of their potent cytotoxicity and implies their potential in producing diversified antitumor or pesticidal constituents.
学科主题	Science & Technology - Other Topics
WOS标题词	Science & Technology
类目[WOS]	Multidisciplinary Sciences
研究领域[WOS]	Science & Technology - Other Topics
关键词[WOS]	CHAETOMIUM-GLOBOSUM ; ENDOPHYTIC FUNGUS ; NATURAL-PRODUCTS ; METABOLITES ; ASPERGILLUS ; CHAETOMUGILINS ; BIOASSAY
收录类别	SCI
原文出处	10.1007/s11434-012-5442-2
语种	英语
WOS记录号	WOS:000321952900005
公开日期	2014-07-17
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/16533]
专题	海洋研究所_实验海洋生物学重点实验室
通讯作者	Zhang, Y
作者单位	1.Dalian Univ Technol, Sch Life Sci & Biotechnol, Dalian 116024, Peoples R China 2.Dalian Jiaotong Univ, Sch Environm & Chem Engn, Dalian 116028, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Zhang Yi,Mu Jun,Feng Yan,et al. Biological and chemical diversity of cytotoxin-producing symbiotic marine fungi in intertidal zone of Dalian[J]. CHINESE SCIENCE BULLETIN,2013,58(19):2290-2297.
APA	Zhang Yi,Mu Jun,Feng Yan,Li HeNan,Dong XueWei,&Zhang, Y.(2013).Biological and chemical diversity of cytotoxin-producing symbiotic marine fungi in intertidal zone of Dalian.CHINESE SCIENCE BULLETIN,58(19),2290-2297.
MLA	Zhang Yi,et al."Biological and chemical diversity of cytotoxin-producing symbiotic marine fungi in intertidal zone of Dalian".CHINESE SCIENCE BULLETIN 58.19(2013):2290-2297.