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	Two new withanolides from the halophyte Datura stramonium L.
	Fang, Sheng-Tao1; Liu, Xia1,2; Kong, Na-Na1,2; Liu, Su-Jing1; Xia, Chuan-Hai1
刊名	NATURAL PRODUCT RESEARCH
	2013-11-01
卷号	27期号:21页码:1965-1970
关键词	Datura stramonium halophyte withanolides steroids
ISSN号	1478-6419
通讯作者	Xia, CH (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai 264003, Peoples R China. chxia@yic.ac.cn
产权排序	[Fang, Sheng-Tao; Liu, Xia; Kong, Na-Na; Liu, Su-Jing; Xia, Chuan-Hai] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai 264003, Peoples R China; [Liu, Xia; Kong, Na-Na] Univ Chinese Acad Sci, Coll Resources & Environm, Beijing 100049, Peoples R China
中文摘要	Eight steroids, including five withanolides (1-5) and three other ergostane-type steroids (6-8), were isolated from the aerial parts of the halophyte Datura stramonium L., which were collected from the Yellow River Delta in China. Their structures were elucidated on the basis of extensive spectroscopic methods, especially 1D and 2D NMR techniques. Compounds 1 and 2 were new compounds and characterised as (22R)-27-hydroxy-7-methoxy-1-oxowitha-3,5,24-trienolide and its 27-O--d-glucopyranoside. Compound 3 was a new natural product and identified as (22R)-27-hydroxy-1-oxowitha-2,5,24-trienolide and isolated from nature for the first time.
英文摘要	Eight steroids, including five withanolides (1-5) and three other ergostane-type steroids (6-8), were isolated from the aerial parts of the halophyte Datura stramonium L., which were collected from the Yellow River Delta in China. Their structures were elucidated on the basis of extensive spectroscopic methods, especially 1D and 2D NMR techniques. Compounds 1 and 2 were new compounds and characterised as (22R)-27-hydroxy-7-methoxy-1-oxowitha-3,5,24-trienolide and its 27-O--d-glucopyranoside. Compound 3 was a new natural product and identified as (22R)-27-hydroxy-1-oxowitha-2,5,24-trienolide and isolated from nature for the first time.
学科主题	Chemistry, Applied ; Chemistry, Medicinal
研究领域[WOS]	Chemistry ; Pharmacology & Pharmacy
收录类别	SCI
原文出处	http://dx.doi.org/10.1080/14786419.2013.800981
语种	英语
WOS记录号	WOS:000327834100005
公开日期	2014-07-08
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/7043]
专题	烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Coll Resources & Environm, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Fang, Sheng-Tao,Liu, Xia,Kong, Na-Na,et al. Two new withanolides from the halophyte Datura stramonium L.[J]. NATURAL PRODUCT RESEARCH,2013,27(21):1965-1970.
APA	Fang, Sheng-Tao,Liu, Xia,Kong, Na-Na,Liu, Su-Jing,&Xia, Chuan-Hai.(2013).Two new withanolides from the halophyte Datura stramonium L..NATURAL PRODUCT RESEARCH,27(21),1965-1970.
MLA	Fang, Sheng-Tao,et al."Two new withanolides from the halophyte Datura stramonium L.".NATURAL PRODUCT RESEARCH 27.21(2013):1965-1970.

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