Patterning Surfaces for Controlled Platelet Adhesion and Detection of Dysfunctional Platelets

	Patterning Surfaces for Controlled Platelet Adhesion and Detection of Dysfunctional Platelets
	Ye W ; Shi Q ; Wong SC ; Hou JW ; Shi HC ; Yin JH
刊名	macromolecular bioscience
	2013
卷号	13 期号:6 页码:676-681
关键词	2-METHACRYLOYLOXYETHYL PHOSPHORYLCHOLINE GRAFT-POLYMERIZATION GLYCOPROTEIN IIB/IIIA PHOSPHOLIPID POLYMER WHOLE-BLOOD IN-VITRO TIROFIBAN INHIBITION
ISSN号	1616-5187
通讯作者	shi q
中文摘要	platelets play a fundamental role in thrombus formation and in the pathogenesis of arterial thrombosis. patterning surfaces for controlled platelet adhesion paves the way for adhesion and activation mechanisms in platelets and detection of platelet functional defects. here, a new and simple method based on controlled polymerization of 2-methacryloyloxyethyl phosphorylcholine (mpc) on the surface of styrene-block-(ethylene-co-butylene)-block-styrene (sebs) is shown. the competition between polymerization and degradation enables platelet adhesion on sebs to be switched on and off. the adhesive sites of the platelets can be down to single cell level, and the dysfunctional platelets can be quantitatively detected.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000320590500003
公开日期	2014-04-15
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/49827]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Ye W,Shi Q,Wong SC,et al. Patterning Surfaces for Controlled Platelet Adhesion and Detection of Dysfunctional Platelets[J]. macromolecular bioscience,2013,13(6):676-681.
APA	Ye W,Shi Q,Wong SC,Hou JW,Shi HC,&Yin JH.(2013).Patterning Surfaces for Controlled Platelet Adhesion and Detection of Dysfunctional Platelets.macromolecular bioscience,13(6),676-681.
MLA	Ye W,et al."Patterning Surfaces for Controlled Platelet Adhesion and Detection of Dysfunctional Platelets".macromolecular bioscience 13.6(2013):676-681.