A Facile One-Pot Synthesis of Copper Sulfide-Decorated Reduced Graphene Oxide Composites for Enhanced Detecting of H2O2 in Biological Environments

	A Facile One-Pot Synthesis of Copper Sulfide-Decorated Reduced Graphene Oxide Composites for Enhanced Detecting of H2O2 in Biological Environments
	Bai J ; Jiang XE
刊名	analytical chemistry
	2013
卷号	85 期号:17 页码:8095-8101
关键词	HYDROGEN-PEROXIDE BIOSENSOR REACTIVE OXYGEN DIRECT ELECTROCHEMISTRY HORSERADISH-PEROXIDASE QUANTUM DOTS ELECTRON-TRANSFER CARBON ELECTRODE AG NANOPARTICLES VISIBLE-LIGHT CYTOCHROME-C
ISSN号	0003-2700
通讯作者	jiang xe
中文摘要	the high levels of h2o2 are closely associated with cancer and progressive neurodegenerative diseases, such as parkinson's disease. in this study, we developed a novel cus nanoparticle-decorated reduced graphene oxide-based electrochemical biosensor for the reliable detection of h2o2. the new electrocatalyst, cus/rgo composites was successfully prepared by heating the mixture of cucl2 and na2s aqueous solutions in the presence of pvp-protected graphene oxide at 180 degrees c. a potential application of cus/rgo composite-modified electrode as a biosensor to monitor h2o2 has been investigated. the steady-state current response increases linearly with h2o2 concentration from 5 to 1500 mu m with a fast response time of less than 2 s. the detection limit (3 sigma) for determination of h2o2 has been estimated to be 0.27 mu m, which was lower than certain enzymes and noble metal nanomaterial-based biosensors. in addition, the study of storage time on the amperometric response of the sensor indicates super stability. due to these remarkable analytical advantages, the as-made sensor was applied to determine the h2o2 levels in human serum and urine samples and h2o2 released from human cervical cancer cells with satisfactory result this new nanocomposite with the high surface area and electrocatalytic activity is a promising candidate for use as an enhanced electrochemical sensing platform in the design of nonenzymatic biosensors.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000330017300013
公开日期	2014-04-15
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/49625]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Bai J,Jiang XE. A Facile One-Pot Synthesis of Copper Sulfide-Decorated Reduced Graphene Oxide Composites for Enhanced Detecting of H2O2 in Biological Environments[J]. analytical chemistry,2013,85(17):8095-8101.
APA	Bai J,&Jiang XE.(2013).A Facile One-Pot Synthesis of Copper Sulfide-Decorated Reduced Graphene Oxide Composites for Enhanced Detecting of H2O2 in Biological Environments.analytical chemistry,85(17),8095-8101.
MLA	Bai J,et al."A Facile One-Pot Synthesis of Copper Sulfide-Decorated Reduced Graphene Oxide Composites for Enhanced Detecting of H2O2 in Biological Environments".analytical chemistry 85.17(2013):8095-8101.