Synthesis of Electroactive and Biodegradable Multiblock Copolymers Based on Poly(ester amide) and Aniline Pentamer

	Synthesis of Electroactive and Biodegradable Multiblock Copolymers Based on Poly(ester amide) and Aniline Pentamer
	Song L ; Du BG ; Chen L ; Deng MX ; Sun H ; Pang X ; Zhang PB ; Chen XS
刊名	journal of polymer science part a-polymer chemistry
	2013
卷号	51 期号:22 页码:4722-4731
关键词	RING-OPENING POLYMERIZATION AMINO-ACID BLOCK-COPOLYMER ELECTRICAL-STIMULATION CONDUCTING POLYMER CELL-ADHESION POLYLACTIDE FUNCTIONALIZATION HYDROGELS BIOMATERIALS
ISSN号	0887-624x
通讯作者	deng mx
中文摘要	a new family of multiblock copolymers (pea-b-ap) based on poly(ester amide) (pea) and aniline pentamer (ap) with the unique properties of being both electroactive and biodegradable was synthesized via a two-stage active solution polycondensation. the new synthesis approach proceeded smoothly, and avoided the complicated purification steps for separating the intermediate products. the molecular weight of pea blocks was regulated by varying the nucleophilic/electrophilic monomers feed ratios. the chemical structures of the copolymers were confirmed by both ir and nmr spectra. uv-vis spectroscopy indicated that the copolymers possessed of the intrinsic electroactivity of ap blocks, and showed three reversible oxidation states. the copolymers had lower degradation rates than the pea homopolymers with similar molecular weight, and their degradation rates were greatly affected by the proportion of ap blocks. in vitro cell culture studies of the pea-b-aps revealed that they facilitated the proliferation of rsc96 schwann cells and displayed a good biocompatibility. these biodegradable copolymers with electroactive function may have great potential for use as nerve repair and regeneration scaffold materials in tissue engineering. (c) 2013 wiley periodicals, inc. j. polym. sci., part a: polym. chem. 2013, 51, 4722-4731
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000325462600002
公开日期	2014-04-15
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/49469]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Song L,Du BG,Chen L,et al. Synthesis of Electroactive and Biodegradable Multiblock Copolymers Based on Poly(ester amide) and Aniline Pentamer[J]. journal of polymer science part a-polymer chemistry,2013,51(22):4722-4731.
APA	Song L.,Du BG.,Chen L.,Deng MX.,Sun H.,...&Chen XS.(2013).Synthesis of Electroactive and Biodegradable Multiblock Copolymers Based on Poly(ester amide) and Aniline Pentamer.journal of polymer science part a-polymer chemistry,51(22),4722-4731.
MLA	Song L,et al."Synthesis of Electroactive and Biodegradable Multiblock Copolymers Based on Poly(ester amide) and Aniline Pentamer".journal of polymer science part a-polymer chemistry 51.22(2013):4722-4731.