Two new ylangene-type sesquiterpenoids from cultures of the fungus Postia sp.
Fan, Qiong-Ying1; Dong, Ze-Jun2; Li, Zheng-Hui2; Yin, Xia2; Yang, Xiao-Yan2; Feng, Tao2; Wei, Kun2; Liu, Ji-Kai2; Zhao, Bao-Hua1
刊名JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
2014-03-04
卷号16期号:3页码:254-258
关键词Postia sp ylangene-type sesquiterpenoids bioactivity protein tyrosine phosphatase inhibitory activity
ISSN号1028-6020
通讯作者Liu,JK (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 654201,Peoples R China. ; jkliu@mail.kib.ac.cn ; zhaobaohua@mail.hebtu.edu.cn
英文摘要Two new ylangene-type sesquiterpenoids, postinins A (1) and B (2), were isolated from cultures of the fungus Postia sp. Structures 1 and 2 were elucidated on the basis of extensive spectroscopic analysis. The bioactivity evaluation showed that both compounds had significant inhibitory activities against protein tyrosine phosphatase 1B, and SH2-containing cytoplasmic tyrosine phosphatase-1 and -2 with IC50 values of 1.6-6.2g/ml.
学科主题Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
类目[WOS]Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]PHOSPHATASE
收录类别SCI ; IC
资助信息National Natural Science Foundation of China [81102348, U1132607]
语种英语
WOS记录号WOS:000329899200004
公开日期2014-04-09
内容类型期刊论文
源URL[http://ir.kib.ac.cn/handle/151853/17938]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Hebei Normal Univ, Coll Life Sci, Shijiazhuang 050024, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 654201, Peoples R China
推荐引用方式
GB/T 7714
Fan, Qiong-Ying,Dong, Ze-Jun,Li, Zheng-Hui,et al. Two new ylangene-type sesquiterpenoids from cultures of the fungus Postia sp.[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2014,16(3):254-258.
APA Fan, Qiong-Ying.,Dong, Ze-Jun.,Li, Zheng-Hui.,Yin, Xia.,Yang, Xiao-Yan.,...&Zhao, Bao-Hua.(2014).Two new ylangene-type sesquiterpenoids from cultures of the fungus Postia sp..JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,16(3),254-258.
MLA Fan, Qiong-Ying,et al."Two new ylangene-type sesquiterpenoids from cultures of the fungus Postia sp.".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 16.3(2014):254-258.
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