Chemical Progress in Cyclopeptide-containing Traditional Medicines Cited in Chinese Pharmacopoeia

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Chemical Progress in Cyclopeptide-containing Traditional Medicines Cited in Chinese Pharmacopoeia
	Zhao Simeng 1,2; Kuang Bin 1,2; Peng Wenwen 1,2; He Wenjun 1; Xu Huimin 1,2; Ji Changjiu 1,2; Han Jing 1,2; Zheng Yuqing 1,2; Song Weiwu 1,2; Tan Ninghu 1
刊名	CHINESE JOURNAL OF CHEMISTRY
	2012-06-01
卷号	30 期号:6 页码:1213-1225
关键词	cyclopeptide traditional Chinese medicine chemical constituent
ISSN号	1001-604X
通讯作者	Tan, NH (reprint author), Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China,nhtan@mail.kib.ac.cn
英文摘要	Plant cyclopeptides, cyclic compounds formed mainly by the peptidic bonds of 237 protein and non-protein amino acids (mainly L-amino acids) and found in higher plants, have been attractive for their extensive bioactivities and distinctive molecular architectures. During the last half century's study, about 500 cyclopeptides divided into eight types have been isolated from over 120 species, which belong to over 20 families and 60 genera. Some cyclopeptides showed potential anti-tumor, sedative, immunosuppressive, and uterotonic activities. In the Chinese Pharmacopoeia (CP, 2010 Version), 23 species (14 families, 18 genera) containing cyclopeptides have been recorded in the origins of 24 traditional Chinese medicines (TCMs). Heterophyllin B (64), first reported by us from Pseudostellaria heterophylla in 1993 was cited for the first time in CP as the standard substance of cyclopeptides for quality control. In this review, we highlight the progress in the chemical studies of these cyclopeptide-containing TCMs, in particular recent results in our group's publications.
学科主题	Chemistry
类目[WOS]	Chemistry, Multidisciplinary
研究领域[WOS]	Chemistry
关键词[WOS]	HIGHLY OXYGENATED NORTRITERPENOIDS ; VIOLA-YEDOENSIS MAKINO ; CYCLIC-PEPTIDES ; LEONURUS-HETEROPHYLLUS ; ZIZYPHUS-JUJUBA ; STELLARIA-DICHOTOMA ; VACCARIA-SEGETALIS ; RUBIA-YUNNANENSIS ; ARDISIA-CRENATA ; ASTER-TATARICUS
收录类别	SCI
资助信息	This work was supported by the National Natural Science Foundation of China (No. U1032602, 91013002, 30725048), the National New Drug Innovation Major Project of China (No. 2011ZX09307-002-02), and the National Basic Research Program of China (No. 2009CB522300).
语种	英语
WOS记录号	WOS:000305389200004
公开日期	2014-04-02
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/17601]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhao Simeng,Kuang Bin,Peng Wenwen,et al. Chemical Progress in Cyclopeptide-containing Traditional Medicines Cited in Chinese Pharmacopoeia[J]. CHINESE JOURNAL OF CHEMISTRY,2012,30(6):1213-1225.
APA	Zhao Simeng.,Kuang Bin.,Peng Wenwen.,He Wenjun.,Xu Huimin.,...&Tan Ninghu.(2012).Chemical Progress in Cyclopeptide-containing Traditional Medicines Cited in Chinese Pharmacopoeia.CHINESE JOURNAL OF CHEMISTRY,30(6),1213-1225.
MLA	Zhao Simeng,et al."Chemical Progress in Cyclopeptide-containing Traditional Medicines Cited in Chinese Pharmacopoeia".CHINESE JOURNAL OF CHEMISTRY 30.6(2012):1213-1225.