DNA Translocation through Hydrophilic Nanopore in Hexagonal Boron Nitride

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	DNA Translocation through Hydrophilic Nanopore in Hexagonal Boron Nitride
	Zhou, Z ; Hu, Y ; Wang, H ; Xu, Z ; Wang, WL ; Bai, XD ; Shan, XY ; Lu, XH
刊名	SCIENTIFIC REPORTS
	2013
卷号	3
ISSN号	2045-2322
通讯作者	Shan, XY (reprint author), Chinese Acad Sci, Beijing Natl Lab Condensed Matter Phys, Beijing 100190, Peoples R China.
中文摘要	Ultra-thin solid-state nanopore with good wetting property is strongly desired to achieve high spatial resolution for DNA sequencing applications. Atomic thick hexagonal boron nitride (h-BN) layer provides a promising two-dimensional material for fabricating solid-state nanopores. Due to its good oxidation resistance, the hydrophilicity of h-BN nanopore device can be significantly improved by UV-Ozone treatment. The contact angle of a KCl-TE droplet on h-BN layer can be reduced from 57 degrees to 26 degrees after the treatment. Abundant DNA translocation events have been observed in such devices, and strong DNA-nanopore interaction has been revealed in pores smaller than 10 nm in diameter. The 1/f noise level is closely related to the area of suspended h-BN layer, and it is significantly reduced in smaller supporting window. The demonstrated performance in h-BN nanopore paves the way towards base discrimination in a single DNA molecule.
资助信息	Chinese Academy of Sciences; NSFC [61027011]; National Basic Research Program of China [2012CB933002]
语种	英语
公开日期	2014-01-16
内容类型	期刊论文
源URL	[http://ir.iphy.ac.cn/handle/311004/56897]
专题	物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文
推荐引用方式 GB/T 7714	Zhou, Z,Hu, Y,Wang, H,et al. DNA Translocation through Hydrophilic Nanopore in Hexagonal Boron Nitride[J]. SCIENTIFIC REPORTS,2013,3.
APA	Zhou, Z.,Hu, Y.,Wang, H.,Xu, Z.,Wang, WL.,...&Lu, XH.(2013).DNA Translocation through Hydrophilic Nanopore in Hexagonal Boron Nitride.SCIENTIFIC REPORTS,3.
MLA	Zhou, Z,et al."DNA Translocation through Hydrophilic Nanopore in Hexagonal Boron Nitride".SCIENTIFIC REPORTS 3(2013).