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Growing behavior of cells on single-walled carbon nanotubes nonwoven films
Meng, J ; Song, L ; Meng, J ; Kong, H ; Wang, CY ; Zhu, GJ ; Xu, LH ; Xie, SS ; Xu, HY
刊名CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
2007
卷号28期号:3页码:476
ISSN号0251-0790
中文摘要Carbon nanotubes have attracted intensive interests in biomedical research in recent years. In this paper, a novel type of carbon nanotubes material so called nonwoven single walled carbon nanotubes(nonwoven SWNT) with nanotopographic structure and macroscopic volume was used as cell growing scaffold. The morphology and surface chemistry of nonwoven SWNT were observed and characterized by scanning electron microscopy(SEM) and X-ray photoelectron spectroscopy(XPS) respectively. The cells were cultivated in nonwoven SWNT and in other types of substrate as the control. The cells, growth behavior including adhesion, proliferation and cytoskeletal development was investigated by using cell viability assay and confocal observation. The experimental results indicate that nonwoven SWNT exhibited a significant enhancement to the cells adhesion and proliferation in at least 3 weeks. Numerous and well organized cytoskeletal structures were observed when the cells were cultured in nonwoven SWNT. Additionally, an obvious promotional influence of the cells cultivated in nonwoven SWNT scaffold upon the proliferation of those growing in the other. kind of substrate through cell-cell communication were found. The results obtained in this work are of significance to in vitro cell amplification. in a large scale, tissue regeneration or guided repair, as well as biomedical device application.
收录类别SCI
公开日期2013-09-17
内容类型期刊论文
源URL[http://ir.iphy.ac.cn/handle/311004/38863]  
专题物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文
推荐引用方式
GB/T 7714
Meng, J,Song, L,Meng, J,et al. Growing behavior of cells on single-walled carbon nanotubes nonwoven films[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2007,28(3):476.
APA Meng, J.,Song, L.,Meng, J.,Kong, H.,Wang, CY.,...&Xu, HY.(2007).Growing behavior of cells on single-walled carbon nanotubes nonwoven films.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,28(3),476.
MLA Meng, J,et al."Growing behavior of cells on single-walled carbon nanotubes nonwoven films".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 28.3(2007):476.
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