Fabrication of high-quality submicron Nb/Al-AlOx/Nb tunnel junctions | |
Yu, HF ; Cao, WH ; Zhu, XB ; Yang, HF ; Yu, HW ; Ren, YF ; Gu, CZ ; Chen, GH ; Zhao, SP | |
刊名 | CHINESE PHYSICS B
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2008 | |
卷号 | 17期号:8页码:3083 |
关键词 | MACROSCOPIC QUANTUM STATES JOSEPHSON-JUNCTION SUPERPOSITION |
ISSN号 | 1674-1056 |
通讯作者 | Zhao, SP: Chinese Acad Sci, Inst Phys, Beijing Natl Lab Condensed Matter Phys, Beijing 100080, Peoples R China. |
中文摘要 | A mathematical model is proposed to illustrate the activation of STIM1 (stromal interaction molecule 1) protein, the assembly and activation of calcium-release activated calcium (CRAC) channels in T cells. In combination with De Young-Keizer-Li-Rinzel model, we successfully reproduce a sustained Ca(2+) oscillation in cytoplasm. Our results reveal that Ca(2+) Oscillation dynamics in cytoplasm can be significantly affected by the way how the Orail CRAC channel are assembled and activated. A low sustained Ca(2+) influx is observed through the CRAC channels across the plasma membrane. In particular, our model shows that a tetrameric channel complex can effectively regulate the total quantity of the channels and the ratio of the active channels to the total channels, and a period of Ca(2+) oscillation about 29 s is in agreement with published experimental data. The bifurcation analyses illustrate the different dynamic properties between our mixed Ca(2+) feedback model and the single positive or negative feedback models. (c) 2008 Elsevier B.V. All rights reserved. |
收录类别 | SCI |
资助信息 | National Natural Science Foundation of China [10474129, 10534060]; Ministry of Science and Technology of China [2006CB601007, 2006CB921107] |
语种 | 英语 |
公开日期 | 2013-09-17 |
内容类型 | 期刊论文 |
源URL | [http://ir.iphy.ac.cn/handle/311004/37930] ![]() |
专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
推荐引用方式 GB/T 7714 | Yu, HF,Cao, WH,Zhu, XB,et al. Fabrication of high-quality submicron Nb/Al-AlOx/Nb tunnel junctions[J]. CHINESE PHYSICS B,2008,17(8):3083. |
APA | Yu, HF.,Cao, WH.,Zhu, XB.,Yang, HF.,Yu, HW.,...&Zhao, SP.(2008).Fabrication of high-quality submicron Nb/Al-AlOx/Nb tunnel junctions.CHINESE PHYSICS B,17(8),3083. |
MLA | Yu, HF,et al."Fabrication of high-quality submicron Nb/Al-AlOx/Nb tunnel junctions".CHINESE PHYSICS B 17.8(2008):3083. |
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