Development of CaZn based glassy alloys as potential biodegradable bone graft substitute

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	Development of CaZn based glassy alloys as potential biodegradable bone graft substitute
	Jiao, W ; Li, HF ; Zhao, K ; Bai, HY ; Wang, YB ; Zheng, YF ; Wang, WH
刊名	JOURNAL OF NON-CRYSTALLINE SOLIDS
	2011
卷号	357 期号:22-23 页码:3830
关键词	BULK METALLIC GLASSES SIMULATED BODY-FLUID IN-VIVO CORROSION MAGNESIUM ALLOYS MAGNETIC-SUSCEPTIBILITY RARE-EARTH CALCIUM CELLS VITRO ZINC
ISSN号	0022-3093
通讯作者	Zheng, YF: Peking Univ, Dept Adv Mat & Nanotechnol, Coll Engn, Beijing 100871, Peoples R China.
中文摘要	We report the development of a CaZn based bulk glassy alloy (BGA) with combining properties of low Young's modulus, high fracture strength, good corrosion resistance and cytocompatibility, which make it be potential as biodegradable bone graft substitute. Compared to commonly investigated biodegradable metals, the Young's modulus of the BGA is closer to that of cortical bone, and its fracture strength reaches 600 MPa, which is 2 times higher than that of pure magnesium. The magnetic susceptibility of the CaZn based BGA is as low as 22.3 x 10(-6), which is compatible with magnetic resonance imaging (MRI) diagnosis. The BGAs also show slow degradation rate and good cytocompatibility. The new class of biodegradable CaZn based BGAs enriches the family of biomaterials, and the work has implications for developing new biodegradable alloys with active elements. The formation and the origins of excellent properties of the BGA are discussed. (C) 2011 Elsevier B.V. All rights reserved.
收录类别	SCI
资助信息	NSF of China [50731008, 50921091]; MOST of China [2007CB613904, 2010CB731600]
语种	英语
公开日期	2013-09-17
内容类型	期刊论文
源URL	[http://ir.iphy.ac.cn/handle/311004/35886]
专题	物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文
推荐引用方式 GB/T 7714	Jiao, W,Li, HF,Zhao, K,et al. Development of CaZn based glassy alloys as potential biodegradable bone graft substitute[J]. JOURNAL OF NON-CRYSTALLINE SOLIDS,2011,357(22-23):3830.
APA	Jiao, W.,Li, HF.,Zhao, K.,Bai, HY.,Wang, YB.,...&Wang, WH.(2011).Development of CaZn based glassy alloys as potential biodegradable bone graft substitute.JOURNAL OF NON-CRYSTALLINE SOLIDS,357(22-23),3830.
MLA	Jiao, W,et al."Development of CaZn based glassy alloys as potential biodegradable bone graft substitute".JOURNAL OF NON-CRYSTALLINE SOLIDS 357.22-23(2011):3830.