Deactivation of A549 cancer cells in vitro by a dielectric barrier discharge plasma needle

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	Deactivation of A549 cancer cells in vitro by a dielectric barrier discharge plasma needle
	Huang, J ; Chen, W ; Li, H ; Wang, XQ ; Lv, GH ; Khosa, ML ; Guo, M ; Feng, KC ; Wang, PY ; Yang, SZ
刊名	JOURNAL OF APPLIED PHYSICS
	2011
卷号	109 期号:5
关键词	ATMOSPHERIC-PRESSURE PLASMA HEPATOCELLULAR-CARCINOMA BIOMEDICAL APPLICATIONS BACTERIA OXYGEN TORCH INJECTION MIXTURES MEDICINE MELANOMA
ISSN号	0021-8979
通讯作者	Huang, J: Chinese Acad Sci, Inst Phys, Beijing 100190, Peoples R China.
中文摘要	An inactivation mechanism study on A549 cancer cells by means of a dielectric barrier discharge plasma needle is presented. The neutral red uptake assay provides a quantitative estimation of cell viability after plasma treatment. Experimental results show that the efficiency of argon plasma for the inactivation process is very dependent on power and treatment time. A 27 W power and 120 s treatment time along with 900 standard cubic centimeter per minute Ar flow and a nozzle-to-sample separation of 3 mm are the best parameters of the process. According to the argon emission spectra of the plasma jet and the optical microscope images of the A549 cells after plasma treatment, it is concluded that the reactive species (for example, OH and O) in the argon plasma play a major role in the cell deactivation. (C) 2011 American Institute of Physics. [doi:10.1063/1.3553873]
收录类别	SCI
资助信息	National Natural Science Foundation of China [10735090, 11005151]
语种	英语
公开日期	2013-09-17
内容类型	期刊论文
源URL	[http://ir.iphy.ac.cn/handle/311004/35629]
专题	物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文
推荐引用方式 GB/T 7714	Huang, J,Chen, W,Li, H,et al. Deactivation of A549 cancer cells in vitro by a dielectric barrier discharge plasma needle[J]. JOURNAL OF APPLIED PHYSICS,2011,109(5).
APA	Huang, J.,Chen, W.,Li, H.,Wang, XQ.,Lv, GH.,...&Yang, SZ.(2011).Deactivation of A549 cancer cells in vitro by a dielectric barrier discharge plasma needle.JOURNAL OF APPLIED PHYSICS,109(5).
MLA	Huang, J,et al."Deactivation of A549 cancer cells in vitro by a dielectric barrier discharge plasma needle".JOURNAL OF APPLIED PHYSICS 109.5(2011).