Comparative analysis of the three-dimensional structure of Periplaneta fuliginosa densovirus

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	Comparative analysis of the three-dimensional structure of Periplaneta fuliginosa densovirus
	Li, L ; Chen, DH ; Zhou, ZH ; Zhang, JM ; Hu, YY
刊名	CHINESE SCIENCE BULLETIN
	2003
卷号	48 期号:3 页码:277
关键词	PARVOVIRUS VIRUS ORGANIZATION RESOLUTION EXPRESSION GENOME
ISSN号	1001-6538
通讯作者	Hu, YY: Wuhan Univ, Inst Virol, Wuhan 430072, Peoples R China.
中文摘要	The three-dimensional structure of Periplaneta fuliginosa densovirus (pfDNV) is determined at 2.3 nm resolution using the techniques of cryo-electron microscopy and image reconstruction. The pfDNV contains five structural proteins and 60 protein subunits arranged on a T = 1 icosahedral shell with a relatively smooth surface. Its reconstruction reveals its distinct capsid structure from those observed in CPV and GrnDNV. As in GmDNV, spike-like protrusions are not present in pfDNV at the threefold axes; while two small thorn-like protrusions are identified there. However, different from CPV and GmDNV, cylindrical channels along the fivefold axes are closed in pfDNV; while a small thorn-like protrusions, which have not been reported in other parvovirus, are observed there in pfDNV although their function is yet to be investigated. The pfDNV has dimple-like depressions at the icosahedral twofold axes; but has no canyon-like regions encircling the fivefold axes. The icosahedrally well-ordered nucleic acid has also been observed in pfDNV, suggesting that the protein and nucleic acid probably form closed interaction.
收录类别	SCI
语种	英语
公开日期	2013-09-17
内容类型	期刊论文
源URL	[http://ir.iphy.ac.cn/handle/311004/34933]
专题	物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文
推荐引用方式 GB/T 7714	Li, L,Chen, DH,Zhou, ZH,et al. Comparative analysis of the three-dimensional structure of Periplaneta fuliginosa densovirus[J]. CHINESE SCIENCE BULLETIN,2003,48(3):277.
APA	Li, L,Chen, DH,Zhou, ZH,Zhang, JM,&Hu, YY.(2003).Comparative analysis of the three-dimensional structure of Periplaneta fuliginosa densovirus.CHINESE SCIENCE BULLETIN,48(3),277.
MLA	Li, L,et al."Comparative analysis of the three-dimensional structure of Periplaneta fuliginosa densovirus".CHINESE SCIENCE BULLETIN 48.3(2003):277.