Brownian dynamics simulation of directional sliding of histone octamers caused by DNA bending

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	Brownian dynamics simulation of directional sliding of histone octamers caused by DNA bending
	Li, W ; Dou, SX ; Xie, P ; Wang, PY
刊名	PHYSICAL REVIEW E
	2006
卷号	73 期号:5
关键词	INDIVIDUAL NUCLEOSOMES CHROMATIN CORE DISRUPTION RESOLUTION REVEALS COMPLEX RSC
ISSN号	1539-3755
通讯作者	Wang, PY: Chinese Acad Sci, Inst Phys, Lab Soft Matter Phys, Beijing Natl Lab Condensed Matter Phys, Beijing 100080, Peoples R China.
中文摘要	Chromatin-remodeling complexes such as SWI/SNF and RSC of yeast can perturb the structure of nucleosomes in an ATP-dependent manner. Experimental results prove that this chromatin remodeling process involves DNA bending. We simulate the effect of DNA bending, caused by chromatin-remodeling complexes, on directional sliding of histone octamers by Brownian dynamics simulation. The simulation results show that, after a DNA loop being generated at the side of a nucleosome, the histone octamer slides towards this DNA loop until the loop disappears. The DNA loop size is an important factor affecting the process of directional sliding of the histone octamer.
收录类别	SCI
语种	英语
公开日期	2013-09-17
内容类型	期刊论文
源URL	[http://ir.iphy.ac.cn/handle/311004/34354]
专题	物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文
推荐引用方式 GB/T 7714	Li, W,Dou, SX,Xie, P,et al. Brownian dynamics simulation of directional sliding of histone octamers caused by DNA bending[J]. PHYSICAL REVIEW E,2006,73(5).
APA	Li, W,Dou, SX,Xie, P,&Wang, PY.(2006).Brownian dynamics simulation of directional sliding of histone octamers caused by DNA bending.PHYSICAL REVIEW E,73(5).
MLA	Li, W,et al."Brownian dynamics simulation of directional sliding of histone octamers caused by DNA bending".PHYSICAL REVIEW E 73.5(2006).