General and efficient synthesis of 2,3-unsubstituted indoles catalyzed by acidic mesoporous molecular sieves

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	General and efficient synthesis of 2,3-unsubstituted indoles catalyzed by acidic mesoporous molecular sieves
	Sun N(孙楠)1; Hong LF(洪灵芬)1; Huang, Fang 1; Ren H(任鸿)1; Mo WM(莫卫民)1; Hu BX(胡宝祥)1; Shen ZL(沈振陆)1; Hu XQ(胡信全)1,2
刊名	Tetrahedron
	2013
卷号	69 期号:19 页码:3927-3933
关键词	2,3-Unsubstituted indoles N-Benzyl 2-anilinoacetals Heterogeneous catalysis MCM-41-SO3H mesoporous molecular sieve Shape/size selectivity
ISSN号	0040-4020
通讯作者	胡信全
英文摘要	A general and efficient method for the synthesis of 2,3-unsubstituted indoles has been established by the intramolecular cyclization of N-benzyl 2-anilinoacetals. Acidic mesoporous molecular sieve (MCM-41-SO₃H) has shown excellent catalytic activity on this transformation, and the 2,3-unsubstituted indoles bearing 7-substituent or strong electron-withdrawing substituents also could be achieved by this protocol. Moreover, the heterogeneous catalyst, MCM-41-SO₃H, could be conveniently recovered and reused without obvious loss of the catalytic activity. This work will provide an economic and environmentalbenign method for the construction of various indole derivatives.
学科主题	物理化学与绿色催化
收录类别	SCI
资助信息	the National Natural Science Foundation of China (No. 20772111;20876149);the Key Innovation Team Project of Zhejiang Province, China (No. 2009R50002)
语种	英语
WOS记录号	WOS:000318137300023
公开日期	2014-01-06
内容类型	期刊论文
源URL	[http://210.77.64.217/handle/362003/4969]
专题	兰州化学物理研究所_OSSO国家重点实验室
作者单位	1.Zhejiang Univ Technol, Coll Chem Engn & Mat Sci, Hangzhou 310014, Zhejiang, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China
推荐引用方式 GB/T 7714	Sun N,Hong LF,Huang, Fang,et al. General and efficient synthesis of 2,3-unsubstituted indoles catalyzed by acidic mesoporous molecular sieves[J]. Tetrahedron,2013,69(19):3927-3933.
APA	Sun N.,Hong LF.,Huang, Fang.,Ren H.,Mo WM.,...&Hu XQ.(2013).General and efficient synthesis of 2,3-unsubstituted indoles catalyzed by acidic mesoporous molecular sieves.Tetrahedron,69(19),3927-3933.
MLA	Sun N,et al."General and efficient synthesis of 2,3-unsubstituted indoles catalyzed by acidic mesoporous molecular sieves".Tetrahedron 69.19(2013):3927-3933.