Synthesis and characterization of Fe10BO3/Fe3O4/SiO2 and GdFeO3/Fe3O4/SiO2: nanocomposites of biofunctional materials | |
Narayan S. Hosmane ; Shanmin Gao,[a, b] Xin Liu,[b] Tao Xu,[a] Xuehua Ma,[c] Zheyu Shen,[c] Aiguo Wu,[c] Yinghuai Zhu,[d] and Narayan S. Hosmane*[a] | |
刊名 | Chemistry Open
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2013-05-13 | |
卷号 | 37期号:2页码:88—92 |
通讯作者 | Narayan S. Hosmane |
合作状况 | 李雨桐 |
中文摘要 | Cancer is one of the leading causes of death worldwide; with many different types, it kills thousands of people every day. Various types of treatments have been developed to treat cancer, and new approaches that are currently under investigation include boron neutron capture therapy (BNCT)[1] and gadolinium neutron capture therapy (GdNCT).[2] Neutron capture therapy is primarily used to treat brain tumors, such as glioblastoma, a particularly aggressive type of brain tumor that is difficult to treat by conventional means such as radiation therapy. BNCT and GdNCT involve a bimodal approach to treatment, utilizing a cancer-specific drug and a neutron source (neutron beam). The approach is based on the ability of a boron isotope (10B) to absorb neutrons and emit localized cell-killing particles. The main mechanism that takes place in BNCT is the absorption of a neutron to convert 10B to 11B, with the release of 4He2+, 7Li3+, and energy.[3] The energy that is released can then destroy the tumor cell. Gadolinium also attracted interest for its potential use in neutron capture therapy because it is the element with the highest cross-sectional value for thermal neutrons—2.55 105 b and 6.10 104 b for 157Gd and 155Gd, respectively.[4] In fact, the thermal neutron value of 157Gd (2.55 105 b) is 65 times that of 10B, and it releases Auger electrons, internal conversion electrons, g-ray and X-ray after the capture of a single thermal neutron.[1, 5–7] |
学科主题 | 材料科学 |
原文出处 | SCI收录 |
公开日期 | 2013-12-16 |
内容类型 | 期刊论文 |
源URL | [http://ir.nimte.ac.cn/handle/174433/9910] ![]() |
专题 | 宁波材料技术与工程研究所_宁波所知识产出 |
推荐引用方式 GB/T 7714 | Narayan S. Hosmane,Shanmin Gao,[a, b] Xin Liu,[b] Tao Xu,[a] Xuehua Ma,[c] Zheyu Shen,[c] Aiguo Wu,[c] Yinghuai Zhu,[d] and Narayan S. Hosmane*[a]. Synthesis and characterization of Fe10BO3/Fe3O4/SiO2 and GdFeO3/Fe3O4/SiO2: nanocomposites of biofunctional materials[J]. Chemistry Open,2013,37(2):88—92. |
APA | Narayan S. Hosmane,&Shanmin Gao,[a, b] Xin Liu,[b] Tao Xu,[a] Xuehua Ma,[c] Zheyu Shen,[c] Aiguo Wu,[c] Yinghuai Zhu,[d] and Narayan S. Hosmane*[a].(2013).Synthesis and characterization of Fe10BO3/Fe3O4/SiO2 and GdFeO3/Fe3O4/SiO2: nanocomposites of biofunctional materials.Chemistry Open,37(2),88—92. |
MLA | Narayan S. Hosmane,et al."Synthesis and characterization of Fe10BO3/Fe3O4/SiO2 and GdFeO3/Fe3O4/SiO2: nanocomposites of biofunctional materials".Chemistry Open 37.2(2013):88—92. |
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