Multifunctional Fe3O4-TiO2 nanocomposites for magnetic resonance imaging and potential photodynamic therapy

CORC > 宁波材料技术与工程研究所 > 中国科学院宁波材料技术与工程研究所 > 宁波所知识产出

	Multifunctional Fe3O4-TiO2 nanocomposites for magnetic resonance imaging and potential photodynamic therapy
	Wu AG(吴爱国) ; Leyong Zeng,a Wenzhi Ren,a Lingchao Xiang,a Jianjun Zheng,b Bin Chenb and Aiguo Wu*a
刊名	Nanoscale
	2013-01-21
卷号	3 期号:5 页码:2107—2113
通讯作者	吴爱国
合作状况	李雨桐
中文摘要	Multifunctional Fe3O4–TiO2 nanocomposites with Janus structure for magnetic resonance imaging (MRI) and potential photodynamic therapy (PDT) were synthesized, in which Fe3O4 was used as a MRI contrast agent and TiO2 as an inorganic photosensitizer for PDT. Their morphology, structure, and MRI and PDT performance were characterized, respectively. Moreover, the location of Fe3O4–TiO2 nanocomposites in MCF-7 cells was also investigated by the staining of Prussian blue and alizarin red, respectively. The results showed that the as-prepared Fe3O4–TiO2 nanocomposites had good T2-weighted MRI performance, and the MCF-7 cells incubated with nanocomposites could be killed under the irradiation of UV light. Compared with traditional organic photosensitizers, TiO2 inorganic photosensitizers could have more stable PDT performance due to their nanoscale size and anti-photodegradable stability. Therefore, the as-prepared Fe3O4–TiO2 nanocomposites could have potential applications as a new kind of multifunctional agent for both MRI and PDT.
学科主题	材料科学
原文出处	SCI收录
公开日期	2013-12-16
内容类型	期刊论文
源URL	[http://ir.nimte.ac.cn/handle/174433/9785]
专题	宁波材料技术与工程研究所_宁波所知识产出
推荐引用方式 GB/T 7714	Wu AG,Leyong Zeng,a Wenzhi Ren,a Lingchao Xiang,a Jianjun Zheng,b Bin Chenb and Aiguo Wu*a. Multifunctional Fe3O4-TiO2 nanocomposites for magnetic resonance imaging and potential photodynamic therapy[J]. Nanoscale,2013,3(5):2107—2113.
APA	Wu AG,&Leyong Zeng,a Wenzhi Ren,a Lingchao Xiang,a Jianjun Zheng,b Bin Chenb and Aiguo Wu*a.(2013).Multifunctional Fe3O4-TiO2 nanocomposites for magnetic resonance imaging and potential photodynamic therapy.Nanoscale,3(5),2107—2113.
MLA	Wu AG,et al."Multifunctional Fe3O4-TiO2 nanocomposites for magnetic resonance imaging and potential photodynamic therapy".Nanoscale 3.5(2013):2107—2113.