Fingerprint analysis of Codonopsis radix by HPLC coupled with chemometrics analysis

CORC > 兰州化学物理研究所 > 中国科学院兰州化学物理研究所 > 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室

	Fingerprint analysis of Codonopsis radix by HPLC coupled with chemometrics analysis
	Chen FF(陈方方); Qi HY(戚欢阳); Shi YP(师彦平)
刊名	中草药(英文版)
	2013
卷号	5 期号:4 页码:307-312
关键词	chemometrics Codonopsis Radix fingerprinting analysis HPLC quality control
ISSN号	1674-6384
通讯作者	师彦平
中文摘要	Objective To establish a validated high performance liquid chromatography (HPLC) for the fingerprint analysis of Codonopsis Radix and for the determination of lobetyolin. Methods HPLC coupled with diode array detection method was employed to establish the fingerprint profile and quantitative determination of lobetyolin in Codonopsis Radix. Principal component analysis method was employed to analyze the 52 Codonopsis Radix samples. Results The reference chromatogram was generated with 25 common peaks showing good separation from adjacent peaks. Conclusion Statistical analysis of the obtained data demonstrates that the developed HPLC fingerprint combined with chemometric is a reliable method for the similar evaluation and quality assessment of Codonopsis Radix, and other traditional Chinese herbs.
资助信息	National Natural Science Foundation of China (21075127;20875095)
语种	英语
公开日期	2013-12-11
内容类型	期刊论文
源URL	[http://210.77.64.217/handle/362003/4640]
专题	兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
推荐引用方式 GB/T 7714	Chen FF,Qi HY,Shi YP. Fingerprint analysis of Codonopsis radix by HPLC coupled with chemometrics analysis[J]. 中草药(英文版),2013,5(4):307-312.
APA	Chen FF,Qi HY,&Shi YP.(2013).Fingerprint analysis of Codonopsis radix by HPLC coupled with chemometrics analysis.中草药(英文版),5(4),307-312.
MLA	Chen FF,et al."Fingerprint analysis of Codonopsis radix by HPLC coupled with chemometrics analysis".中草药(英文版) 5.4(2013):307-312.