Cooperative Catalysis with Aldehydes and Copper: Development and Application in Aerobic Oxidative CH Amination at Room Temperature

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	Cooperative Catalysis with Aldehydes and Copper: Development and Application in Aerobic Oxidative CH Amination at Room Temperature
	Xie YJ(谢银君); Qian B(钱波); Jie P(解攀); Huang HM(黄汉民)
刊名	Advanced Synthesis and Catalysis
	2013
卷号	355 期号:7 页码:1315-1322
关键词	aldehydes C—H amination cooperative catalysis copper room temperature reaction
ISSN号	1615-4150
通讯作者	黄汉民
英文摘要	A conceptually new cooperative catalytic system via a synergistic combination of aldehyde and copper catalysis has been established based on systemic mechanistic studies. This new cooperative catalysis has been successfully applied in the direct aerobic oxidative C—H amination of azoles at room temperature, which was previously realized under harsh conditions. Mechanistic studies including isotopic labeling experiments and kinetic isotope effect (KIE) experiments support a reaction pathway that involves formation of an aminal, hydrolysis of the aminal to generate the copper-amide species, subsequent C—H amination and re-oxidation of copper(I) to copper(II) by oxygen. It not only provides an efficient method to realize the oxidative C—H amination of benzoxazoles with free amines at room temperature, but also paves the way for establishing new C—N bond formation reactions by using this efficient cooperative catalysis.
学科主题	物理化学与绿色催化
收录类别	SCI
资助信息	the Chinese Academy of Sciences;the National Natural Science Foundation of China (21222203;21172226;21133011)
语种	英语
WOS记录号	WOS:000318762100014
公开日期	2013-12-18
内容类型	期刊论文
源URL	[http://210.77.64.217/handle/362003/4779]
专题	兰州化学物理研究所_OSSO国家重点实验室
作者单位	Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China
推荐引用方式 GB/T 7714	Xie YJ,Qian B,Jie P,et al. Cooperative Catalysis with Aldehydes and Copper: Development and Application in Aerobic Oxidative CH Amination at Room Temperature[J]. Advanced Synthesis and Catalysis,2013,355(7):1315-1322.
APA	Xie YJ,Qian B,Jie P,&Huang HM.(2013).Cooperative Catalysis with Aldehydes and Copper: Development and Application in Aerobic Oxidative CH Amination at Room Temperature.Advanced Synthesis and Catalysis,355(7),1315-1322.
MLA	Xie YJ,et al."Cooperative Catalysis with Aldehydes and Copper: Development and Application in Aerobic Oxidative CH Amination at Room Temperature".Advanced Synthesis and Catalysis 355.7(2013):1315-1322.