Sequential Scan-Based High-Resolution 3-D Open-Sided Magnetic Particle Imaging System
He, Jie3,4; Zhang, Haoran3,4; Lei, Siao3,4; Li, Guanghui3,4; Li, Yimeng3,4; Zhu, Tao1,2; Qian, Zhumei3,4; Xiong, Fei3,4; Feng, Yuan3,4; An, Yu3,4
刊名IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
2024
卷号73页码:12
关键词Coils Permanent magnets Motors Superparamagnetic iron oxide nanoparticles Spatial resolution Magnetic fields Interference Field-free line (FFL) magnetic particle imaging (MPI) open-sided sequential scan
ISSN号0018-9456
DOI10.1109/TIM.2024.3396830
通讯作者An, Yu(yuan1989@buaa.edu.cn) ; Tian, Jie(tian@ieee.org)
英文摘要Magnetic particle imaging (MPI) is an emerging molecular imaging technique that relies on the nonlinear magnetization response of superparamagnetic iron oxide nanoparticles. Open-sided MPI (OS-MPI) has attracted considerable interest for its potential to enhance interventional procedures. However, improving the spatial resolution of OS-MPI poses a significant challenge, mainly due to the inefficiencies of selection coils in generating, rotating, and shifting a high-gradient field-free line (FFL). To address this issue, we propose a novel approach called the permanent magnet-based sequential scan to develop a high-resolution 3-D OS-MPI system with ultralow power consumption. By utilizing permanent magnets, we can create high-gradient selection fields without any power consumption. The sequential scan technique involves rotating the FFL angle by angle and shifting the FFL layer by layer. To maintain thermal stability during sequential scans, we used drive coils wound with hollow copper wires and implemented forced oil cooling. Additionally, measures such as copper shielding, feed-through compensation, and filtering were employed to minimize interference from the permanent magnets, drive coils, and motor drivers. Experimental results demonstrated that the developed system successfully achieved a spatial resolution of 1 mm while operating with an overall low power consumption of 282.16 W.
资助项目National Natural Science Foundation of China
WOS研究方向Engineering ; Instruments & Instrumentation
语种英语
出版者IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
WOS记录号WOS:001226299000001
资助机构National Natural Science Foundation of China
内容类型期刊论文
源URL[http://ir.ia.ac.cn/handle/173211/58676]  
专题自动化研究所_中国科学院分子影像重点实验室
通讯作者An, Yu; Tian, Jie
作者单位1.Univ Chinese Acad Sci, Sch Artificial Intelligence, Beijing 101408, Peoples R China
2.Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
3.Beihang Univ, Key Lab Big Data Based Precis Med, Minist Ind & Informat Technol China, Beijing 100191, Peoples R China
4.Beihang Univ, Sch Engn Med, Sch Biol Sci & Med Engn, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
He, Jie,Zhang, Haoran,Lei, Siao,et al. Sequential Scan-Based High-Resolution 3-D Open-Sided Magnetic Particle Imaging System[J]. IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT,2024,73:12.
APA He, Jie.,Zhang, Haoran.,Lei, Siao.,Li, Guanghui.,Li, Yimeng.,...&Tian, Jie.(2024).Sequential Scan-Based High-Resolution 3-D Open-Sided Magnetic Particle Imaging System.IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT,73,12.
MLA He, Jie,et al."Sequential Scan-Based High-Resolution 3-D Open-Sided Magnetic Particle Imaging System".IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT 73(2024):12.
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