Tracking the Immediate and Short-Term Effects of Continuous Theta Burst Stimulation on Dynamic Brain States

doi:10.1109/TNSRE.2024.3378712

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	Tracking the Immediate and Short-Term Effects of Continuous Theta Burst Stimulation on Dynamic Brain States
	Chen, Chao 1; Guo, Zhidong 1; Peng, Weiwei 2; Wang, Shengpei 3,4; Qiu, Shuang 3,4; Zhang, Jing 5; Chen, Xiaogang 6; He, Huiguang 3,7
刊名	IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
	2024
卷号	32 页码:1386-1396
关键词	Electroencephalography Hidden Markov models Motors Brain Functional magnetic resonance imaging Automation Protocols Continuous theta burst stimulation resting-state EEG hidden Markov model brain state
ISSN号	1534-4320
DOI	10.1109/TNSRE.2024.3378712
通讯作者	Wang, Shengpei(wangshengpei2014@ia.ac.cn) ; Qiu, Shuang(shuang.qiu@ia.ac.cn) ; He, Huiguang(huiguang.he@ia.ac.cn)
英文摘要	Continuous Theta Burst Stimulation (cTBS) has been shown to modulate cortical oscillations and induce cortical inhibitory effects. Electroencephalography (EEG) studies have shown some immediate effects of cTBS on brain activity. To investigate both immediate effects and short-term effects of cTBS on dynamic brain changes, cTBS was applied to 22 healthy participants over their left motor cortex. We recorded eyes-open, resting-state EEG and performance in the Nine-Hole Peg Test (NHPT) before cTBS, immediately after cTBS, and 80 minutes after cTBS. We identified nine states using a Hidden Markov Model (HMM)-based approach to describe the process of dynamic brain changes. The spatial activation, temporal profiles of HMM states and behavioral performance of NHPT were assessed and compared. cTBS altered the temporal profiles of S1-S5 immediately after cTBS and the temporal profiles of S5, S6 and S7 80 min after cTBS. Moreover, cTBS improved motor function of the left hand. State 1 was characterized as the activation of right occipito-temporal area, and NHPT behavioral performance of the left hand positively correlated with the occurrence of state 1, and negatively correlated with the interval time of state 1 after cTBS. The transitions between S1 or S7 and other states showed dynamic reconfiguration during after-effect sustained time after cTBS. These results suggest that the dynamic characteristics of state 1 are potential biomarkers for characterizing the aftereffect changes of cTBS.
资助项目	National Key Research and Development Program of China
WOS关键词	TRANSCRANIAL MAGNETIC STIMULATION ; MOTOR CORTEX ; EEG ; TMS ; VARIABILITY ; CIRCUITS ; STROKE
WOS研究方向	Engineering ; Rehabilitation
语种	英语
出版者	IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
WOS记录号	WOS:001193979400002
资助机构	National Key Research and Development Program of China
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/58038]
专题	类脑智能研究中心_神经计算及脑机交互
通讯作者	Wang, Shengpei; Qiu, Shuang; He, Huiguang
作者单位	1.Tianjin Univ Technol, Key Lab Complex Syst Control Theory & Applicat, Tianjin 300387, Peoples R China 2.Shenzhen Univ, Sch Psychol, Shenzhen 518060, Peoples R China 3.Univ Chinese Acad Sci, Chinese Acad Sci, Inst Automat, Lab Brain Atlas & Brain Inspired Intelligence,Key, Beijing 100045, Peoples R China 4.Univ Chinese Acad Sci, Chinese Acad Sci, Inst Automat, Sch Artificial Intelligence, Beijing 100045, Peoples R China 5.Capital Med Univ, Beijing Tiantan Hosp, Neurol Dept, Beijing 100070, Peoples R China 6.Chinese Acad Med Sci & Peking Union Med Coll, Inst Biomed Engn, Tianjin 300192, Peoples R China 7.Univ Chinese Acad Sci, Sch Artificial Intelligence, Beijing 100045, Peoples R China
推荐引用方式 GB/T 7714	Chen, Chao,Guo, Zhidong,Peng, Weiwei,et al. Tracking the Immediate and Short-Term Effects of Continuous Theta Burst Stimulation on Dynamic Brain States[J]. IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING,2024,32:1386-1396.
APA	Chen, Chao.,Guo, Zhidong.,Peng, Weiwei.,Wang, Shengpei.,Qiu, Shuang.,...&He, Huiguang.(2024).Tracking the Immediate and Short-Term Effects of Continuous Theta Burst Stimulation on Dynamic Brain States.IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING,32,1386-1396.
MLA	Chen, Chao,et al."Tracking the Immediate and Short-Term Effects of Continuous Theta Burst Stimulation on Dynamic Brain States".IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING 32(2024):1386-1396.