The article views the forthcoming virtual societies, decentralized society (DeSoc) or metaverse, as cyber-physical social systems, and discusses the key issue of management for such human-centered hybrid systems—the prescription of human behaviors. We build parallel humans with its aggregation—parallel population—to complete that task, where each individual’smental knowledge is cognitivelymodeled by heterogeneous learning, analyzed by generative big data with deep evolutionary reasoning, and prescribed by knowledge convergence with an active recommendation. A case study fromsocial security has validated that our parallel population and parallel human are a feasible and effective way to construct DeSoc or metaverse.