Photocatalytic degradation kinetics and mechanism of antivirus drug-lamivudine in TiO2 dispersion

doi:10.1016/j.jhazmat.2011.09.077

	Photocatalytic degradation kinetics and mechanism of antivirus drug-lamivudine in TiO2 dispersion
	An, Taicheng 4; An, Jibin 1,3,4; Yang, Hai 1,4; Li, Guiying 4; Feng, Huixia 3; Nie, Xiangping 2
刊名	Journal of Hazardous Materials
	2011-12-15
卷号	197 页码:229-236
关键词	Computer viruses Dispersions Efficiency Enzyme kinetics Ion chromatography Kinetics Mechanisms Organic carbon Oxide minerals Surface properties Titanium dioxide Central composite designs Degradation efficiency Degradation intermediates Frontier electron densities Lamivudine Photo catalytic degradation Photocatalytic degradation mechanism Response surface methodology
ISSN号	03043894
DOI	10.1016/j.jhazmat.2011.09.077
英文摘要	Photocatalytic degradation kinetics of antivirus drug-lamivudine in aqueous TiO2 dispersions was systematically optimized by both single-variable-at-a-time and central composite design based on the response surface methodology. Three variables, TiO2 content, initial pH and lamivudine concentration, were selected to determine the dependence of degradation efficiencies of lamivudine on independent variables. Response surface methodology modeling results indicated that degradation efficiencies of lamivudine were highly affected by TiO2 content and initial lamivudine concentration. The highest degradation efficiency was achieved at suitable amount of TiO2 and with maintaining initial lamivudine concentration to a minimum. In addition, the contribution experiments of various primary reactive species produced during the photocatalysis were investigated with the addition of different scavengers and found that hydroxyl radicals was the major reactive species involved in lamivudine degradation in aqueous TiO2. Six degradation intermediates were identified using HPLC/MS/MS, and photocatalytic degradation mechanism of lamivudine was proposed by utilizing collective information from both experimental results of HPLC/MS/MS, ion chromatography as well as total organic carbon and theoretical data of frontier electron densities and point charges. © 2011 Elsevier B.V.
WOS研究方向	Engineering ; Environmental Sciences & Ecology
语种	英语
出版者	Elsevier B.V., Netherlands
WOS记录号	WOS:000298200400029
内容类型	期刊论文
源URL	[http://ir.lut.edu.cn/handle/2XXMBERH/150278]
专题	教务处（创新创业学院）
作者单位	1.Graduate School of Chinese Academy of Sciences, Beijing 100049, China 2.Institute of Hydrobiology, Jinan University, Guangzhou 510632, China; 3.College of Petrochemical Technology, Lanzhou University of Technology, Lanzhou 730050, China; 4.State Key Laboratory of Organic Geochemistry, Guangdong Key Laboratory of Environmental Resources Utilization and Protection, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China;
推荐引用方式 GB/T 7714	An, Taicheng,An, Jibin,Yang, Hai,et al. Photocatalytic degradation kinetics and mechanism of antivirus drug-lamivudine in TiO2 dispersion[J]. Journal of Hazardous Materials,2011,197:229-236.
APA	An, Taicheng,An, Jibin,Yang, Hai,Li, Guiying,Feng, Huixia,&Nie, Xiangping.(2011).Photocatalytic degradation kinetics and mechanism of antivirus drug-lamivudine in TiO2 dispersion.Journal of Hazardous Materials,197,229-236.
MLA	An, Taicheng,et al."Photocatalytic degradation kinetics and mechanism of antivirus drug-lamivudine in TiO2 dispersion".Journal of Hazardous Materials 197(2011):229-236.