Preparation and slow release properties of chitosan/modified ATP composite resins

	Preparation and slow release properties of chitosan/modified ATP composite resins
	Feng, Hui-Xia 2; Zhang, Juan 1,2; Wu, Jie 1
刊名	Gongneng Cailiao/Journal of Functional Materials
	2013-02-15
卷号	44 期号:3 页码:388-392
关键词	Chitosan Drug products Encapsulation Adsorption capacities Composite resins Encapsulation efficiency Higuchi equation Morphology and structures O-ATP Release performance Slow release
ISSN号	10019731
英文摘要	This paper prepared chitosan/modified attapulgite resins by curing using NaOH then crosslinking using glutaraldehyde. The morphology and structure of resins were characterized by FT-IR and TG. The adsorption capacity and release performance of the resins which were prepared using chitosan and different kind of modified ATP were discussed with Aspirin as a model drug. The effects of the glutaraldehyde on the adsorption capacity and release performance of resins were studied, and drug release curve of the best resin was fitted by dynamic models. The results showed that among three kinds of resin, the adsorption and drug release capacities of CS/O-ATP were the best. Its drug loading and encapsulation efficiency were 12.2% and 39.88% respectively and also the slow-release effect was good, when the glutaraldehyde was 6mL. The drug release process of CS/O-ATP was better fitted by Higuchi equation, suggested that the resin could be a long-term drug control-released system.
语种	中文
出版者	Journal of Functional Materials, P.O. Box 1512, Chongqing, 630700, China
内容类型	期刊论文
源URL	[http://ir.lut.edu.cn/handle/2XXMBERH/113722]
专题	教务处（创新创业学院）
作者单位	1.Jiangsu Provincial Key Laboratory of Attapulgite Science and Applied Technology, College of Bioengineering and Chemical Engineering, Huaiyin Institute of Technology, Huaian 223003, China 2.College of Petrochemical Technology, Lanzhou University of Technology, Lanzhou 730050, China;
推荐引用方式 GB/T 7714	Feng, Hui-Xia,Zhang, Juan,Wu, Jie. Preparation and slow release properties of chitosan/modified ATP composite resins[J]. Gongneng Cailiao/Journal of Functional Materials,2013,44(3):388-392.
APA	Feng, Hui-Xia,Zhang, Juan,&Wu, Jie.(2013).Preparation and slow release properties of chitosan/modified ATP composite resins.Gongneng Cailiao/Journal of Functional Materials,44(3),388-392.
MLA	Feng, Hui-Xia,et al."Preparation and slow release properties of chitosan/modified ATP composite resins".Gongneng Cailiao/Journal of Functional Materials 44.3(2013):388-392.