A Mixed Micellar Liquid Chromatography with Direct Injection for Rapid Analysis of Eight Sulfonamides in Milk

doi:10.1007/s12161-020-01733-3

	A Mixed Micellar Liquid Chromatography with Direct Injection for Rapid Analysis of Eight Sulfonamides in Milk
	Duan, Xiaoyun 1,2; Liu, Xiaofeng 2; Dong, Yue 1; Duan, Tianjiao 2; Zhang, Jing 1; He, Shujuan 1; Yang, Fatang 1; Dong, Yuming 1
刊名	Food Analytical Methods
	2020-05-01
卷号	13 期号:5 页码:1148-1158
关键词	Additives Amides Dairies Direct injection Liquids Micelles Nonionic surfactants Polyethylene oxides Separation Sodium dodecyl sulfate Sulfur compounds Chromatographic systems Limit of quantitations Micellar liquid chromatography Mobile phase additives Polyoxyethylene lauryl ethers Retention mechanism Sodium dodecyl sulfate solutions Three-phase equilibria
ISSN号	19369751
DOI	10.1007/s12161-020-01733-3
英文摘要	In this work, an isocratic mixed micellar liquid chromatography method was first applied to the separation of eight sulfonamides in milk. Mixed anionic and nonionic surfactants were used as mobile phase additives. Because proteins in the milk can be dissolved by the micelles, the milk samples can be directly injected into the chromatographic system after being simply diluted 10 times with 0.1 M sodium dodecyl sulfate solution. Besides, three-phase equilibrium theory was firstly used to explain the retention mechanism of sulfonamides in the mixed micellar liquid chromatography. The optimized mobile phase was an aqueous solution (0.04 M sodium dodecyl sulfate and 0.01 M polyoxyethylene lauryl ether) containing 20 mM NaH2PO4 with 10% (v/v) of n-propanol at pH 3.0. The separation was performed on a Venusil XBP C18 column (250 × 4.6 mm, i.d., 5 μm). The proposed mixed micellar liquid chromatography method was validated in terms of linear ranges (20–2500 μg/L), limit of detections (1.9–8.0 μg/L), limit of quantitations (6.1–27 μg/L), recoveries (84–105%), intra- and inter-precisions (RSD © 2020, Springer Science+Business Media, LLC, part of Springer Nature.
WOS研究方向	Food Science & Technology
语种	英语
出版者	Springer
WOS记录号	WOS:000517683100002
内容类型	期刊论文
源URL	[http://ir.lut.edu.cn/handle/2XXMBERH/151039]
专题	生命科学与工程学院
作者单位	1.School of Pharmacy, Lanzhou University, Lanzhou, China; 2.School of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, China
推荐引用方式 GB/T 7714	Duan, Xiaoyun,Liu, Xiaofeng,Dong, Yue,et al. A Mixed Micellar Liquid Chromatography with Direct Injection for Rapid Analysis of Eight Sulfonamides in Milk[J]. Food Analytical Methods,2020,13(5):1148-1158.
APA	Duan, Xiaoyun.,Liu, Xiaofeng.,Dong, Yue.,Duan, Tianjiao.,Zhang, Jing.,...&Dong, Yuming.(2020).A Mixed Micellar Liquid Chromatography with Direct Injection for Rapid Analysis of Eight Sulfonamides in Milk.Food Analytical Methods,13(5),1148-1158.
MLA	Duan, Xiaoyun,et al."A Mixed Micellar Liquid Chromatography with Direct Injection for Rapid Analysis of Eight Sulfonamides in Milk".Food Analytical Methods 13.5(2020):1148-1158.