Clinical mid-term outcomes of the Chinese-made CL-V bileaflet mechanical heart valve in Chinese patients

doi:10.21037/jtd-20-2644

	Clinical mid-term outcomes of the Chinese-made CL-V bileaflet mechanical heart valve in Chinese patients
	Qi, Liang 2,3; Liu, Shidong 2,3; Qiang, Yan 1,4; Zhao, Honglin 2; Liu, Ruisheng 2; Cheng, Dianwei 2; Song, Bing 2; Guan, Quanlin 3
刊名	JOURNAL OF THORACIC DISEASE
	2021
卷号	13 期号:1 页码:10-17
关键词	Heart valve disease CL-V bileaflet mechanical heart valve St. Jude Medical heart valve
ISSN号	2072-1439
DOI	10.21037/jtd-20-2644
英文摘要	Background: The CL-V full-carbon bileaflet mechanical heart valve is a novel Chinese-made prosthetic valve. This study evaluated the mid-term outcomes of the CL-V bileaflet mechanical heart valve after implantation in Chinese patients. Methods: This study retrospectively enrolled a total of 38 consecutive patients who underwent elective mechanical heart valve replacement (MHVR) with two different valve types from April 2004 and May 2010, including 18 patients with the CL-V bileaflet mechanical heart valve (44.4% male, mean age 47.4 +/- 6.2 years, mean body weight 64.7 +/- 11.9 kg) and 20 patients with the St. Jude mechanical heart valve (45.0% male, mean age 49.7 +/- 7.6 years, mean body weight 66.1 +/- 11.1 kg). All patients underwent follow-up clinical evaluations in the outpatient department at all-time points. Results: No complications occurred during the mean 61.3 months follow-up time (range, 47- 102 months). The cardiothoracic ratios (52.7%+/- 4.5% vs. 50.1%+/- 4.0%), left atrium diameter (46.5 +/- 7.6 vs. 44.8 +/- 9.3 mm), left ventricular diastolic diameter (47.6 +/- 4.9 vs. 48.2 +/- 8.5 mm) and left ventricular ejection fraction (65.4%+/- 8.7% vs. 64.5%+/- 8.0%) were not significantly different between the two groups (P>0.05). Transthoracic Doppler echocardiography showed that the hemodynamic indexes were not significantly different between the two groups at 1 year and 3 years (P>0.05). Furthermore, no significant differences were found between the two groups in hemocompatibility indexes at both 6 months and 3 years postoperatively (P>0.05). Conclusions: The mid-term follow-up results of the CL-V bileaflet mechanical heart valve were similar to those of the St. Jude Medical heart valve, which showed stable hemodynamics and good blood compatibility. Chinese-made CL-V bileaflet mechanical heart valves can be a substitute for St. Jude Medical heart valves, and can be widely used in cardiac surgery.
WOS研究方向	Respiratory System
语种	英语
出版者	AME PUBL CO
WOS记录号	WOS:000614747100002
内容类型	期刊论文
源URL	[http://ir.lut.edu.cn/handle/2XXMBERH/147483]
专题	能源与动力工程学院
作者单位	1.Lanzhou Univ Technol, Energy & Power Engn Coll, Lanzhou, Peoples R China; 2.Lanzhou Univ, Dept Cardiovasc Surg, Hosp 1, Lanzhou 730000, Peoples R China; 3.Lanzhou Univ, Sch Clin Med 1, Lanzhou, Peoples R China; 4.Southeast Univ, Sch Energy & Environm, Nanjing, Peoples R China
推荐引用方式 GB/T 7714	Qi, Liang,Liu, Shidong,Qiang, Yan,et al. Clinical mid-term outcomes of the Chinese-made CL-V bileaflet mechanical heart valve in Chinese patients[J]. JOURNAL OF THORACIC DISEASE,2021,13(1):10-17.
APA	Qi, Liang.,Liu, Shidong.,Qiang, Yan.,Zhao, Honglin.,Liu, Ruisheng.,...&Guan, Quanlin.(2021).Clinical mid-term outcomes of the Chinese-made CL-V bileaflet mechanical heart valve in Chinese patients.JOURNAL OF THORACIC DISEASE,13(1),10-17.
MLA	Qi, Liang,et al."Clinical mid-term outcomes of the Chinese-made CL-V bileaflet mechanical heart valve in Chinese patients".JOURNAL OF THORACIC DISEASE 13.1(2021):10-17.