Factors influencing artemisinin production from shoot cultures of Artemisia annua L

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	Factors influencing artemisinin production from shoot cultures of Artemisia annua L
	Liu, C. Z. ; Guo, C. ; Wang, Y. C. ; Fan, O. Y.
刊名	World Journal of Microbiology & Biotechnology
	2003
期号	5 页码:535-538
关键词	artemisinin biosynthesis Artemisia annua L. biomass plant-based valuable metabolite production shoot culture hairy root cultures qinghaosu artemisinin suspension-cultures antimalarial drug ginseng saponin tissue-cultures improved growth panax-ginseng sucrose light
其他题名	World J. Microbiol. Biotechnol.
中文摘要	Artemisinin, an anti-malarial drug isolated from the annual wormwood Artemisia annua L., has a marked activity against chloroquine-resistant and chloroquine-sensitive strains of Plasmodium falciparum, and is useful in treatment of cerebral malaria. Shoot cultures of Artemisia annua L. were established on Murashige and Skoog basal medium which contained (per litre) 30 g sucrose, 0.5 mg 6-benzyladenine and 0.05 mg naphthaleneacetic acid. Using an optimized combination of sucrose (30 g/l), nitrate (45 mM), inorganic phosphate (200 mg/l), gibberellic acid (7 mg/l) and the ratio of NH4+-N to NO3--N of 1:3, artemisinin production reached 26.7 mg/l after 30 days. This procedure provides a potential alternative for production of artemisinin from in vitro tissue cultures.
收录类别	SCI
原文出处	://WOS:000184717300014
语种	英语
公开日期	2013-11-08
内容类型	期刊论文
版本	出版稿
源URL	[http://ir.ipe.ac.cn/handle/122111/5290]
专题	过程工程研究所_研究所（批量导入）
推荐引用方式 GB/T 7714	Liu, C. Z.,Guo, C.,Wang, Y. C.,et al. Factors influencing artemisinin production from shoot cultures of Artemisia annua L[J]. World Journal of Microbiology & Biotechnology,2003(5):535-538.
APA	Liu, C. Z.,Guo, C.,Wang, Y. C.,&Fan, O. Y..(2003).Factors influencing artemisinin production from shoot cultures of Artemisia annua L.World Journal of Microbiology & Biotechnology(5),535-538.
MLA	Liu, C. Z.,et al."Factors influencing artemisinin production from shoot cultures of Artemisia annua L".World Journal of Microbiology & Biotechnology .5(2003):535-538.