Research progress of biodegradable polymers/drug nanoparticles prepared by supercritical fluid technology

doi:10.11949/0438-1157.20190852

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	Research progress of biodegradable polymers/drug nanoparticles prepared by supercritical fluid technology
	Zhan, Shiping 1,2; Ding, Shiqiang 1,2; Wang, Weijing 2; Li, Mingming 2; Zhao, Qicheng 2
刊名	Huagong Xuebao/CIESC Journal
	2020-03-01
卷号	71 期号:3 页码:923-935
关键词	Diagnosis Drug delivery Effluent treatment Emulsification Environmental technology Functional polymers Nanoparticles Purification Supercritical fluidsDevelopment directions Granulation technology Preparation technology Rapid expansion of supercritical solutions Separation and purification Supercritical anti-solvent precipitations Supercritical fluid technology Technological characteristics
ISSN号	04381157
DOI	10.11949/0438-1157.20190852
英文摘要	Biodegradable polymers/drug nanoparticles have outstanding advantages in the fields of the drug targeted delivery, effective component encapsulation and medical diagnosis and so on. The nanoparticles preparation technologies from supercritical fluid have been widely studied because of its green environmental protection, many kinds of preparation methods, easy to adjust product quality according to the requirements of use, easy subsequent separation and purification, and so on. In order to obtain polymer/drug nanoparticles to meet the requirements, supercritical fluid granulation technology is one of the effective methods. The characteristics and applications of biodegradable polymer materials were discussed. Supercritical fluid and its characteristics were briefly introduced. The technological characteristics, preparing methods, basic principle and research progress on the rapid expansion of supercritical solution (RESS), supercritical anti-solvent precipitation (SAS), supercritical CO2 assisted atomization (SAA) and supercritical fluid emulsion extraction (SFEE) were mainly introduced. The development directions of polymer/drug nanoparticles prepared by supercritical fluid technology were prospected. © All Right Reserved.
语种	中文
出版者	Materials China
内容类型	期刊论文
源URL	[http://ir.lut.edu.cn/handle/2XXMBERH/132333]
专题	兰州理工大学
作者单位	1.College of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou; Gansu; 730050, China; 2.College of Environmental and Chemical Engineering, Dalian University, Dalian; Liaoning; 116622, China
推荐引用方式 GB/T 7714	Zhan, Shiping,Ding, Shiqiang,Wang, Weijing,et al. Research progress of biodegradable polymers/drug nanoparticles prepared by supercritical fluid technology[J]. Huagong Xuebao/CIESC Journal,2020,71(3):923-935.
APA	Zhan, Shiping,Ding, Shiqiang,Wang, Weijing,Li, Mingming,&Zhao, Qicheng.(2020).Research progress of biodegradable polymers/drug nanoparticles prepared by supercritical fluid technology.Huagong Xuebao/CIESC Journal,71(3),923-935.
MLA	Zhan, Shiping,et al."Research progress of biodegradable polymers/drug nanoparticles prepared by supercritical fluid technology".Huagong Xuebao/CIESC Journal 71.3(2020):923-935.