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Chemical constituents and cytotoxic activity of Gentiana farreri Balf.f
Yang, Ai Mei1,2; Li, Hui1; Sun, Jing1; Wu, Rui1; Guo, Weijie1
2013
会议日期December 22, 2012 - December 23, 2012
会议地点Beihai, China
关键词Aldehydes Industrial engineering Production engineering Chemical constituents Cytotoxic activities Gentiana farreri Balf.f Herb medicine Hydroxyacetophenones MTT assays
卷号655-657
DOI10.4028/www.scientific.net/AMR.655-657.1945
页码1945-1948
英文摘要Six compounds were isolated from Gentiana farrerii, which was used as traditonal herb medicine in the treatment of some diseases. Their structures were identified as: linoleic acid(1), dibutyl-phthalate(2), p-hydroxy benzaldehyde (3), hydroxyacetophenone (4), isoscoparin (5), 5,7,3',4'-tetrahydroxyflavone-6-β-D-glucopyranoside(6). All compounds were isolated from Gentiana farrerii for the first time. The cytotoxic activity on the growth of HepG-2 cells of all compounds were investigated in MTT assay, the results showed that compound 2, 5, 6 have weak cytotoxic activity, IC50 is 41.26, 96.74, 99.33 (μg/ml), respectively. © (2013) Trans Tech Publications, Switzerland.
会议录Advanced Materials Research
会议录出版者Trans Tech Publications, P.O. Box 1254, Clausthal-Zellerfeld, D-38670, Germany
语种英语
ISSN号10226680
内容类型会议论文
源URL[http://ir.lut.edu.cn/handle/2XXMBERH/117867]  
专题兰州理工大学
作者单位1.College of Life science and Engineering, Lanzhou University of Technology, Lanzhou 730050, China;
2.Institute of Lanzhou Animal Science and Veterinary Pharmaceutics, Chinese Academy of Agricultural Sciences, Gansu Lanzhou, 730050, China
推荐引用方式
GB/T 7714
Yang, Ai Mei,Li, Hui,Sun, Jing,et al. Chemical constituents and cytotoxic activity of Gentiana farreri Balf.f[C]. 见:. Beihai, China. December 22, 2012 - December 23, 2012.
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