Application of Tilapia Skin Acellular Dermal Matrix to Induce Acute Skin Wound Repair in Rats

doi:10.3389/fbioe.2021.792344

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室

	Application of Tilapia Skin Acellular Dermal Matrix to Induce Acute Skin Wound Repair in Rats
	Lv, Kangning 2,3; Wang, Lei 2; He, Xiaoli 1,2; Li, Wenjun 2; Han, Lei 1; Qin, Song 2
刊名	FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
	2022-02-14
卷号	9 页码:10
关键词	tilapia skin acellular dermal matrix collagen wound repair
ISSN号	2296-4185
DOI	10.3389/fbioe.2021.792344
通讯作者	Qin, Song(sqin@yic.ac.cn)
英文摘要	Extracellular matrix (ECM) material with good biological activity is essential to simulate cell growth microenvironment, induce cell infiltration and angiogenesis, and promote the repair of large area acute skin wound. In this study, tilapia skin acellular dermal matrix (TADM) was prepared to simulate ECM microenvironment, which can promote substantial area acute wound healing in rats. The main component of TADM is type I collagen, which has good physical and chemical properties, biological activity and cell adhesion. TADM is a form of biomaterial with low immunogenicity, low risk of prion infection and lower economic cost than other related materials such as mammalian collagen biomaterials. Our results show that TADM can guide cell infiltration, angiogenesis, regulate the expression and secretion of inflammatory and skin repair correlated factors to promote tissue healing.
WOS关键词	ARTIFICIAL SKIN ; COLLAGEN ; CARBODIIMIDE ; GRAFTS ; BURNS
WOS研究方向	Biotechnology & Applied Microbiology ; Science & Technology - Other Topics
语种	英语
WOS记录号	WOS:000761695500001
资助机构	Department of Science and Technology of Shandong Province
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/31504]
专题	海岸带生物学与生物资源利用重点实验室
通讯作者	Qin, Song
作者单位	1.Yantai Univ, Sch Life Sci, Yantai, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai, Peoples R China 3.Yantai Univ, Sch Ocean, Yantai, Peoples R China
推荐引用方式 GB/T 7714	Lv, Kangning,Wang, Lei,He, Xiaoli,et al. Application of Tilapia Skin Acellular Dermal Matrix to Induce Acute Skin Wound Repair in Rats[J]. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY,2022,9:10.
APA	Lv, Kangning,Wang, Lei,He, Xiaoli,Li, Wenjun,Han, Lei,&Qin, Song.(2022).Application of Tilapia Skin Acellular Dermal Matrix to Induce Acute Skin Wound Repair in Rats.FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY,9,10.
MLA	Lv, Kangning,et al."Application of Tilapia Skin Acellular Dermal Matrix to Induce Acute Skin Wound Repair in Rats".FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 9(2022):10.