The distinct toxicity effects between commercial and realistic polystyrene microplastics on microbiome and histopathology of gut in zebrafish

doi:10.1016/j.jhazmat.2022.128874

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 山东省海岸带环境工程技术研究中心

	The distinct toxicity effects between commercial and realistic polystyrene microplastics on microbiome and histopathology of gut in zebrafish
	Guo, Xiaotong 2,5; Lv, Min 1,5; Li, Jinhua 1,5; Ding, Jing 4; Wang, Yunqing 1,5; Fu, Longwen 1,5; Sun, Xiyan 1,5; Han, Xiaoyue 2,5; Chen, Lingxin 1,3,5
刊名	JOURNAL OF HAZARDOUS MATERIALS
	2022-07-15
卷号	434 页码:11
关键词	Realistic microplastics Enrofloxacin Combined exposure Gut microbiome Histological analysis
ISSN号	0304-3894
DOI	10.1016/j.jhazmat.2022.128874
通讯作者	Lv, Min(mlv@yic.ac.cn) ; Chen, Lingxin(lxchen@yic.ac.cn)
英文摘要	As a ubiquitous emerging pollutant, microplastics (MPs) have attracted widespread attention. At this stage, researchers mainly employed commercial MPs (CMPs) as the model particles to explore the toxic effects of MPs. But whether CMPs can reflect the effects of realistic MPs (RMPs) still remains unknown. Herein, the effects of commercial and realistic polystyrene MPs on gut microbiota of zebrafish were compared. Considering MPs co-exist with antibiotics in real environment, we further distinguished the effects of CMPs and RMPs when they co-existed with enrofloxacin (ENR). The results revealed that while both CMPs and RMPs significantly shifted the gut microbiota, CMPs exhibited stronger toxic effects and more severe damage to gut. Furthermore, ENR exhibited a distinct effect with both CMPs and RMPs on gut microbiota, while the addition of CMPs and RMPs significantly alleviated the toxicity of ENR. In addition, analysis via Kyoto Encyclopedia of Genes and Genomes pathway database revealed that seven major level 1 pathways associated with metabolism, information processing and diseases in the microbial community were affected. Taken together, this work is the first to report that CMPs could not represent RMPs in terms of toxicity and other behaviors, reminding people the limits of using CMPs in ecotoxicology studies.
WOS关键词	AQUATIC ORGANISMS ; EXPOSURE ; POLYETHYLENE ; MUSSELS
WOS研究方向	Engineering ; Environmental Sciences & Ecology
语种	英语
WOS记录号	WOS:000793548200004
资助机构	Youth Innovation Pro-motion Association CAS ; National Natural Science Founda-tion of China ; Natural Science Foundation of Shandong Province ; Taishan Scholar Project Special Funding
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/31032]
专题	烟台海岸带研究所_山东省海岸带环境工程技术研究中心
通讯作者	Lv, Min; Chen, Lingxin
作者单位	1.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Pilot Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China 4.Yantai Univ, Sch Environm & Mat Engn, Yantai 264005, Peoples R China 5.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
推荐引用方式 GB/T 7714	Guo, Xiaotong,Lv, Min,Li, Jinhua,et al. The distinct toxicity effects between commercial and realistic polystyrene microplastics on microbiome and histopathology of gut in zebrafish[J]. JOURNAL OF HAZARDOUS MATERIALS,2022,434:11.
APA	Guo, Xiaotong.,Lv, Min.,Li, Jinhua.,Ding, Jing.,Wang, Yunqing.,...&Chen, Lingxin.(2022).The distinct toxicity effects between commercial and realistic polystyrene microplastics on microbiome and histopathology of gut in zebrafish.JOURNAL OF HAZARDOUS MATERIALS,434,11.
MLA	Guo, Xiaotong,et al."The distinct toxicity effects between commercial and realistic polystyrene microplastics on microbiome and histopathology of gut in zebrafish".JOURNAL OF HAZARDOUS MATERIALS 434(2022):11.